Job title: Scientist / Engineer

• Location: Waltham, MA

About the job

The USA-mRNALNP Drug Product Team supports the Formulation and Process Development group in Waltham, MA, and reports to the DPGroup Lab Team Lead. We are seeking an individual with process development and/or formulation and good laboratory skills and scientific understanding of formulation development experience to contribute to bringing innovative new vaccines to the market.

Join the engine of Sanofis mission where deep immunoscience meets bold, AI-powered research. In R&D, youll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi:

Were an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world and are supported and enhanced through our diverse portfolio of medical device and diagnostic products. Together, we chase the miracles of science to improve peoples lives.

Main Responsibilities:

• Lead the formulation optimization and/or process understanding of mRNA-containing lipid nanoparticle (LNP) formulation and production processes encompassing a wide range of different mRNAs and novel lipids.

• Work closely with the Research team in transferring and accelerating new LNP composition formulation into CMC development.

• Design and conduct small-scale multi-component LNP formulating experiments to understand the developability of new LNP formulations.

• Lead the compilation of Developability package for new LNP formulations.

• Develop initial formulation process for new LNP formulations.

• Design and arrange studies to assess the stability of new LNP formulations.

• Performing in-process drug product characterization.

• Perform complex and routine analytical methods to characterize new formulations and to troubleshoot as needed.

• Coordinate/Suggest/Introduce advanced LNP characterization analysis with the Analytical Sciences department

• Support the Drug Product team to troubleshoot technical, formulation, and processing issues

• Document development study set up, results, and conclusions within an electronic lab notebook

• Tabulating and analyzing in-process and post-process characterization data

• Summarize and present study progress, generated data, and analysis to other scientific team members and larger group meetings

• Supporting the growth and expansion goals by setting up and installing new characterization and process equipment into new laboratories

About you

Basic Qualifications

• Bachelor's in Engineering, Pharmaceutical Sciences, or Chemistry related science discipline, with 5 or more years of professional experience in formulation and/or process development

• Master's in engineering, Pharmaceutical Sciences, or Chemistry related science discipline, with 3 or more years of professional experience in formulation and/or process development. Internships and co-ops experience will be considered

• Ph.D. in Engineering, Pharmaceutical Sciences, or Chemistry related science discipline, with a minimum of 6 months of experience in formulation and/or process development.Academic experience will be considered

Key Skills, Abilities, and Competencies

• Strong scientific understanding of formulation and process development in pharmaceutical related environment

• Ability to independently design experiments, analyze complex datasets, and recommend development strategies

• Strong organizational and communication skills with the ability to work and communicate cross-functionally

• General understanding of common LNP production process and analytical characterization techniques is desirable, prior experience running these techniques is a plus

• Desire to work in a fast-paced environment

• Ability to be flexible and responsive to change, be a results-driven problem solver

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave.

• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

• Help improve the lives of millions of people globally by making drug development quicker and more effective.

• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.