Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Sr. Manager Manufacturing - AR5 Solution Prep

What you will do

Lets do this. Lets change the world. In this vital role you will lead the Solution Preparation organization within AR5 a critical and highly integrated part of Amgens large-scale biomanufacturing network. This team plays an essential role in the success of the plant by supplying high-quality media to Cell Culture and buffers to Purification, enabling the reliable and consistent manufacture of Amgens biologic medicines.

The Senior Manager oversees a team of more than 50 staff working across four shifts, each led by a Front-Line Manager, ensuring safe, compliant, and efficient 24/7 operations.

As a member of the AR5 Manufacturing Leadership Team, this leader shapes operational performance, drives site-wide alignment, and plays a key role in transforming how we manufacture today to deliver on the processes of tomorrow.

Key Responsibilities:

Safety and Quality Leadership

• Champion Amgens core commitment to safety and product quality by fostering a culture of accountability and continuous improvement.

• Ensure manufacturing execution consistently meets GMP, EHS, and regulatory expectations, with proactive risk identification and mitigation.

• Strengthen and build upon an already strong safety and quality culture, reinforcing standards through daily leadership presence on the floor (Gemba).

Operational Leadership

• Lead the Solution Preparation organization to achieve production goals across a 24/7 operation.

• Provide oversight and direction to Front-Line Managers, ensuring alignment with AR5s Floor Operating Principles and site objectives.

• Coordinate cross-functional support to troubleshoot and resolve operational challenges, including participation in the AR5/AR30 on-call leadership rotation.

Strategic and Continuous Improvement

• Influence site and network-level manufacturing strategy, driving operational excellence, digital literacy, and adoption of modern manufacturing processes.

• Lead initiatives to reduce deviations, enhance process reliability, and improve right-first-time performance.

• Champion digital and data-driven solutions to improve decision-making, operational transparency, and real-time performance oversight.

Innovation and Process Enhancement

• Drive process transformation efforts that enhance efficiency and eliminate non-value-added activities.

• Lead operational readiness for process improvements, including innovative changeover, scheduling, and resource deployment solutions.

• Support I-530 operations, capacity utilization, and scalability across both AR5 and AR30.

Talent Development

• Mentor and grow Front-Line Managers and staff, fostering engagement, belonging, and a mentality of continuous learning.

• Reinforce Amgens Agile Workforce model and OnePlant philosophy by enabling cross-training and dynamic resource allocation across AR5 and AR30.

• Build an impactful, adaptable organization prepared to meet the evolving demands of a future-ready manufacturing network.

Capacity Planning and Network Collaboration

• Lead resource planning and capacity modeling to align with Amgens long-range manufacturing plan.

• Partner closely with Quality, Process Development, Engineering, Safety, Supply Chain, and Technology to ensure integrated, reliable operations.

• Collaborate across the global Amgen manufacturing network to share best practices, align strategic priorities, and elevate network performance.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dedicated professional we seek is a collaborative partner with these qualifications.

Basic Qualifications:

• High School diploma/GED and 12 years of Manufacturing & Operations experience OR

• Associate's degree and 10 years of Manufacturing & Operations experience OR

• Bachelors degree and 8 years of Manufacturing & Operations experience OR

• Masters degree and 6 years of Manufacturing & Operations experience OR

• Doctorate degree and 2 years of Manufacturing & Operations experience Or

In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above.

Preferred Qualifications:

• Passion for manufacturing, including people and process

• Demonstrated managerial experience in a regulated manufacturing environment

• Familiarity with GMP regulations as they apply to biotechnology manufacturing

• Skilled in change management, team building, and fostering innovation

• Cross-functional work experience in a manufacturing-facing function such as Process Development, Quality, Supply Chain or Engineering

• Excellent communication skills, drive, sense of urgency, and problem-solving abilities

• Demonstrated experience in applying Operational Excellence and Lean Manufacturing

• Demonstrated ability to forge and maintain strong relationships with other functional areas

• User-level fluency with digital tools for daily management, data analysis and visualization, and application of Artificial Intelligence (e.g, Copilot, Chat GPT, etc)

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.