Sr. Technical Program Manager, Infrastructure Engineering
- Employer
- Moderna, Inc.
- Location
- Cambridge, Massachusetts
- Posted date
- Sep 28, 2026
View more categories
- Discipline
- Engineering, Information Technology, Science/R&D, Applications/Technical Support, Information/Data Security, Network Administration, Software Development, System Administration, Machine Learning
- Required Education
- Bachelors Degree
- Position Type
- Full time
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Job Details
The Role:
Moderna is seeking a Senior Technical Program Manager (TPM)to drive project and program management of infrastructure(cloud and on-prem) rationalization and AI-readinessinitiatives at Moderna globally.We’relooking for someone witha high levelof integrity and personal accountability, strong interpersonal skills, and infrastructure technology domainexpertise.
Here’s What You’ll Do
Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting
Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process
Build processes, templates, and structure, orleverageexisting ones as appropriate
Manage vendors, schedule, scope, and cost
Measure program success (or lack thereof) and risks using data and facts
Provide balanced risk remediation strategies and recommendations and drive risk mitigation
Develop andmaintainclose stakeholder relationships and build influence to drive theappropriate outcomesacross Moderna
Provide clear,accurate, consistent, andtimelycommunications
Advance good infrastructure and security practices and culture
Partner Collaborationwork withCloud Engineering, Systems Engineering, and AI Engineering,as well asNetwork Engineering,Identity and Access Management,Builder Tools & Platforms,IT, Cybersecurity,software engineering,and business stakeholders to manage and driveimprovement projectsin a structured and predictable manner
Manage multiple initiatives:
Cloudmodernization
Rationalize infrastructure platforms, tooling, and service models that underpin AI workloads.
Identifyandeliminateredundant, unsupported, or non‑scalable infrastructure patterns that impede AI adoption.
Enable standardized, secure, and supportable “AI‑ready” infrastructure foundations that accelerate time‑to‑value while managing cost and risk.
Ensure infrastructure rationalization aligns with AI governance, data protection, and compliance requirements.
Define and track KPIs related to platform consolidation, cost optimization, risk reduction, and AIenablementreadiness.
Lead and drive infrastructure servicemanagementimprovements and process optimization initiatives, including infrastructure patch and vulnerability management.
Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, andmaintainantiracist policies and processes
Here’s What You’ll Need (Minimum Qualifications)
8+ years of program management experience,preferably ininfrastructureengineering
Demonstrated technical depth, problem-solving capabilities, andstakeholder andvendor management skills
Technical background ininfrastructureengineering, with a strong understanding of ITSM
Experience in running programs within a cross-functional,global team of mixed engineering, architecture, and operations.
Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion
Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback
Proven ability tooperatein highly matrixed environments and influence without direct authority.
Here’s What You’ll Bring to the Table (Preferred Qualifications)
Strong understanding of cloud platforms (AWS,Azure)
Familiarity with infrastructure concepts: compute, storage, networking, containers, Kubernetes
Working knowledge of AI/ML infrastructure needs (GPUs, distributed training, data pipelines,MLOps)
Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders
Deep familiarity with ITSM frameworks (e.g., ITIL)
Experience driving structured, process-driveninfrastructuretransformation initiatives.
Knowledge of security and compliance standards relevant toinfrastructure operations.
Embrace a culture of continuous service improvement and service excellence
A desire to make an impact as part of a high-growth, transformational company
Experience with GxP environments and regulatory requirements
Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.
Competitive healthcare, plus voluntary benefit programs to support your unique needs
A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
Family planning benefits, including fertility, adoption, and surrogacy support
Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
Savings and investments to help you plan for the future
Location-specific perks and extras
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Our Working Model
As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.
Moderna is a smoke-free, alcohol-free, and drug-free work environment.
Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!
Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accommodations
We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com.
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Company
Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.
mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”
Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.
Moderna employees share their thoughts on our culture, values and mission. To hear additional employee stories and learn more about our inclusive and innovative benefits offerings, visit us on our website.
Stock Symbol:
MRNA
Stock Exchange:
USNASDAQ GS
- Phone
- 617-714-6500
- Location
- 200 Technology Square
Cambridge, MA
