The Role

We are seeking a Senior Engineer I to join the Automated Systems Engineering team within Applied Technologies, focused on translating early-stage automation into robust, scalable, GMP-ready solutions for bioassay workflows.

In this role, you will bridge development and regulated environments by hardening automated systems for deployment into GMP settings. You will lead technical execution across the automation lifecycle, including design, integration, testing, deployment, and sustainment, ensuring systems meet requirements for data integrity, traceability, and operational robustness.

This role requires a strong understanding of cell-based bioassays and their constraints under automation, including workflows such as cell maintenance, transfection, assay execution, and sample preparation. You will partner across engineering, assay development, quality, and operations to deliver automation solutions that maintain biological integrity while enabling reliable, high-throughput execution in support of clinical and commercial programs

Here's What You’ll Do

• Lead the development and hardening of automated bioassay workflows, transforming early-stage prototypes into robust, scalable, GMP-ready systems.

• Collaborate with scientists to translate cell-based bioassays and sample preparation workflows into automation solutions, accounting for biological constraints such as cell health, sterility, and timing sensitivity.

• Design and implement automation strategies for cell handling workflows (e.g., maintenance, passaging, transfection, assay execution) to ensure reproducibility and assay integrity at scale.

• Own technical execution across projects, including requirements definition, system integration, testing, deployment, and sustainment.

• Partner cross-functionally with Analytical Development, Applied Technologies, Analytical Sciences & Technology, Digital, and QC Operations to enable successful transfer and deployment of systems into regulated environments.

• Develop automation solutions that meet GMP expectations, including data integrity, traceability, and audit readiness.

• Troubleshoot complex issues across biological performance, liquid handling, and system integration layers, including investigation of assay variability and automation-induced bias.

• Drive standardization and continuous improvement of automation platforms and workflows to support scalability across programs.

Here’s What You’ll Bring to the Table (Basic Qualifications)

• BS with 8 years of relevant experience, MS with 5 years of relevant experience or PhD in Engineering, Biology, Biochemistry, Bioengineering, or related discipline.

• Hands-on experience supporting or working with cell-based bioassays or sample preparation workflows.

• Experience working in or supporting regulated laboratory environments. (GLP/GMP)

• Experience programming and developing with laboratory automation software/hardware and liquid handlers.

• This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Experience supporting or deploying automation systems into GMP or regulated environments, including:

• Experience developing and supporting automation for:

• Experience with 3rd party automation hardware such as cobot arms, decappers, centrifuges, dispensers, sealers/peelers, etc.

• Direct experience configuring and optimizing Hamilton STAR/Vantage automated liquid handling systems.

• Experience with workcell based automation equipment controlled by scheduling software such as HighRes Cellario, Thermo CRS Momentum, etc.

• Success Characteristics

• Demonstrates strong ownership and accountability; delivers high-quality, reliable outcomes

• Collaborates effectively across functions; proactively solves complex problems

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.

• Competitive healthcare, plus voluntary benefit programs to support your unique needs

• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support

• Family planning benefits, including fertility, adoption, and surrogacy support

• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown

• Savings and investments to help you plan for the future

• Location-specific perks and extras

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com. 

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