Company Overview:

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.

Role Summary:

The Medical Science Liaison (MSL) is an experienced field medical expert who plays a strategic role on the field medical team with depth and breadth of business acumen, therapeutic knowledge and serves as an informal leader on the team. The person in this role is a customer facing, field-based extension of our Medical Affairs team. The MSL’s key objective is to create impact through advancing clinical practice within the assigned territory that leads to improved patient outcomes. This individual serves as a key scientific resource, engaging with healthcare professionals (HCPs), key opinion leaders (KOLs), and other stakeholders to provide scientific and clinical support for our portfolio. 

This is a field-based role.

Primary Responsibilities Include:

• Builds awareness of the company within the medical community and develops strategic KOL/territory engagement plans aligned with the medical strategy 

• Supports clinical research (investigator-initiated and company-sponsored), speaker development, and training as needed 

• Demonstrates thorough knowledge of the company, its investigational products, and current medical research 

• Maximizes attendance at national and regional conferences to gather insights, assess the competitive landscape, and strengthen relationships 

• Collaborates cross-functionally (clinical, regulatory, market access) to advance business and scientific goals

• Develops and executes regional medical strategies in alignment with company goals

• Leads KOL engagement strategies and identifying new scientific leaders

• Demonstrates business acumen within therapeutic area and understands broader organization and competitive landscape

• Leads identification and mapping of key KOLs within the therapeutic area, driving engagement strategies

• Provides strategic leadership within the MSL team as a peer leader, motivator, and problem solver

• Manages top-tier KOL relationships, synthesizes high-level medical insights, and informs company medical strategies

• Mentors junior MSLs and contributes to team strategy development

• Acts as a subject matter expert for internal stakeholders, including marketing, sales, and clinical teams

• Collaborates with internal teams (HEOR, access, marketing, sales) to maintain a customer-centric, compliant approach within assigned territory

• Establishes and develops HCP relationships, engaging in activities such as data discussions, clinical trials, and addressing patient journey barriers

• Responds to unsolicited information requests in a timely, accurate, and compliant manner

• Ensures compliant dissemination of scientific and clinical information to healthcare providers

• Manages administrative tasks (e.g., Veeva CRM, expense reports, compliance modules) efficiently, including customer profiling and keeping CRM information up to date

Education and Skills Requirements:

• Advanced scientific degree or equivalent required (e.g., MD, PhD, NP, PharmD, PA)

• 10+ years of MSL experience is preferred

• Clinical experience within neuromuscular disorders (e.g., DMD, DM1) preferred; rare disease experience considered

• Strong knowledge of investigational products and the neuromuscular space, including emerging data

• In-depth understanding of clinical trial and investigator-sponsored study processes

• Proven ability to work effectively within multidisciplinary teams

• Clear understanding of MSL role and responsibilities

• Skilled in building and maintaining relationships with KOLs through scientific expertise and follow-through

• Ability to communicate research results clearly to diverse audiences

• Strong communication skills (written, verbal, presentation) for building relationships with colleagues

• Ability to influence without authority at all levels of the organization and externally 

• Expert in planning, prioritizing, and executing tasks efficiently

• Capable of working independently and managing time in a home office

• Adaptable in ambiguous and dynamic environments

• Leverages past neuromuscular relationships to support study enrollment and site communication

• Experienced in relationship building to expand company reach

• Experience with relationship building and expanding a company’s reach

• Must be willing to travel extensively and occasionally on weekends

• Positive team member who embodies the Dyne Core Values

• Excitement about Dyne’s vision and mission 

• Must be willing to travel extensively and occasionally on weekends

MA Pay Range

$183,000 - $250,000USD

The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.