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Principal Research Scientist, Analytical Chemistry

Employer
IDEAYA Biosciences
Location
South San Francisco, CA
Posted date
Sep 28, 2026
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Job Details

Non-Solicitation Policy and Notice to Agencies and Recruiters:

IDEAYA's Non-Solicitation Policy strictly prohibits agencies and recruiters from any contact and communication with IDEAYA employees, managers, and leaders to submit unsolicited candidate resumes and/or to solicit business partnerships. Submission of unsolicited candidate resumes by agencies or recruiters with or without a contract in place with IDEAYA Biosciences Inc. will not create any implied obligation. Failure to comply with this policy will result in disqualification from current and future business opportunities with IDEAYA Biosciences. All recruiting and talent agency decisions are strictly managed by the internal IDEAYA Human Resources function. All communication by external agencies and recruiters must be directed to humanresources@ideayabio.com. We ask that you only email your interest once.

Job Summary

Job Description

What you’ll do:

  • Oversee small molecule analytical chemistry efforts across the IDEAYA discovery portfolio

  • Manage and execute compound purifications (including chiral SFC separations), structural elucidations, biophysical property determinations (such as solubility, logD, and pKa determinations), and stability studies

  • Manage junior analytical chemist(s) to achieve strong productivity with high quality and scientific rigor

  • Ensure existing methods are technically sound, well developed and fit-for purpose

  • Troubleshoot methods and provide technical guidance across discovery programs

  • Manage installation and maintenance of lab analytical equipment.

  • Perform vendor review and selection and provide oversight of all analytical work at external CROs

  • Proactively communicate with and work closely with other functions to help align analytical strategy and achieve goals

  • Help hire high-caliber analytical chemists as needed to build and grow a world-class analytical department

  • Stay aware of newly emerging techniques and technologies and bring new capabilities online as necessary

Requirements:

  • Ph.D. in analytical chemistry or related discipline with minimum of (5) years of drug discovery experience with demonstrated ability operating successfully within cross-functional groups

  • Strong subject matter expertise in small molecule purification (both HPLC and SFC essential), physicochemical analysis, analytical method development/validation, and CRO management is essential

  • Additional experience with small molecule structural elucidation techniques is preferred

  • Strong problem-solving skills and ability to quickly adapt and shift focus as needed

  • Stronginterpersonal and communication skills and the ability to work within project teams

  • Ability to multi-task in a fast-paced dynamic environment while demonstrating a calm and positive attitude and a superior work ethic

  • Ability to supervise and mentor junior level associates and/or scientists, including direct reports or supporting team members

All employees are expected to act with integrity and in full compliance with applicable laws, regulations, and IDEAYA policies, including IDEAYA’s Code of Conduct.

Employees must demonstrate good judgement and ethical behavior in all business activities, maintain patient and product safety as a top priority, and report any suspected violations of law or Company policy through appropriate channels

Total Rewards

Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs.

The expected salary range for the roleof the Principal Research Scientist, Analytical Chemistry is $167,000 - $206,000. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates’ experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process.

The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.

IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.

By clicking apply, your email address will be shared with the employer.