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Director of GI/Inflammation and Neuroscience- Biologics In Vitro Pharmacology

Employer
Takeda
Location
Boston, Massachusetts
Start date
Feb 4, 2025
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Job Details

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Job Description

Director of GI/Inflammation and Neuroscience- Biologics In Vitro Pharmacology

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Director where you will play a major role in the discovery of novel biologics, contributing to the strategic direction of our GI/Inflammation and Neuroscience research programs.

How you will contribute:

  • Strategic Leadership- Provide strategic direction to the GI/Inflammation and Neuroscience discovery project teams, ensuring alignment with company goals and objectives.
  • Functional Leadership-
    • Oversee the strategy for functional evaluation and candidate selection of novel GI/ Inflammation and Neuroscience therapeutics.
    • Lead a team responsible for the design, development and execution of state-of-the-art in vitro pharmacology assays to evaluate the biological activity, potency, efficacy, and mechanism of action of our novel therapeutics, utilizing cutting-edge technologies (e.g., complex cell-based assays, co-culture systems, and 3D organoid models) to measure cellular responses in inflammatory pathways, and neuronal cell signaling.
    • Develop and implement innovative technologies to elevate our in vitro pharmacology capabilities and throughput to enhance translation and increase quality and efficiency. Stay abreast of the latest scientific advancements and industry trends.
  • Program Leadership: Lead the GI/Inflammation and Neuroscience biologics discovery programs with cross-functional discovery teams, driving the programs from lead ID to preclinical development.
  • Collaboration: Build strong internal and external collaborations, foster alignment with our key stakeholders. Collaborate closely with interdisciplinary research teams in a matrix format, to advance discovery programs.
  • Mentoring: Mentor and develop team members, fostering a culture of innovation, collaboration, and scientific excellence.

Minimum Requirements/Qualifications:

  • PhD degree in immunology or a related scientific discipline with 10+ years’ experience.
  • Minimum of 10 years of experience in GI/Inflammation and Neuroscience research, with at least 7 years industry experience in pharma, biotech with a track record of leading GI/inflammation and Neuroscience discovery projects, specifically in Autoimmune and inflammatory diseases.
  • Minimum of 7 years of management experience.
  • Expertise in biologics drug discovery and development processes, including hit identification, lead optimization, candidate selection, and preclinical development.
  • Proven track record of leading successful in vitro pharmacology efforts in the field of GI/Inflammation and Neuroscience, including assay development and validation, functional screening, and mechanism of action studies.
  • Strong technical proficiency in a wide range of in vitro pharmacology techniques and assay formats, including complex cell-based phenotypic assays, immune cell-based assays, co-culture systems, inflammation-based assays, neuronal models and GI organoid systems, flow cytometry, and high content imaging.
  • Excellent leadership, communication, and interpersonal skills, with the ability to lead a team and projects and collaborate effectively across disciplines, demonstrate enterprise leadership with an ability to influence without authority.
  • Knowledge of regulatory requirements and guidelines for drug discovery and development

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

169,400.00 - 266,200.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time TypeFull time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Company

For over 240 years, Takeda’s propensity to evolve has driven the next generation of innovation. Today, our organization spans the globe—colleagues across business units and functions face challenges head-on to deliver life-transforming treatments, guided by our commitment to patients, our people and the planet.

As a values-based, R&D-driven biopharmaceutical leader headquartered in Japan, we focus our R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. In addition to our R&D efforts, we’re laser-focused on harnessing the power of data, digital, and technology to improve health outcomes for patients across the globe.

 

Since our founding in Japan, integrity and putting patients first have been at the heart of our identity. We're proud of our employees and their commitment to improving the quality of life for patients, and to working with our partners in health care in approximately 80 countries and regions. With each new breakthrough comes opportunities to develop your career, hone new skills, and create a brighter future

For more information, visit https://jobs.takeda.com/

Company info
Website
Location
650 East Kendall Street
Cambridge
MA
02421
United States

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