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Postdoctoral Fellow Emerging Therapeutic Modalities-Induced Proximity Platform

Employer
Amgen
Location
Thousand Oaks, California
Start date
Jan 18, 2025
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Job Details

Job Description

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Postdoctoral Fellow

What you will do

Lets do this. Lets change the world. This is a unique opportunity to be part of Amgens R&D Postdoc Program Center of Excellence in Emerging Therapeutic Modalities located at our global headquarters and research site in Thousand Oaks, California. This vital role will join Research Technologies Department led by Dr. Ryan Potts and train under leading scientists in the field of Induced Proximity.

We are hiring a highly motivated postdoctoral fellow to perform an independent research project as part of a core team of cross-functional scientists and critical thinkers, passionate about the theme of Emerging Therapeutic Modalities. The position is for 2-4 years depending on time to complete projects. Successful candidates will have access to Amgens cutting-edge technologies and innovation and be encouraged to make exciting scientific contributions to the field, present at scientific conferences and publish their work. Postdocs will be a part of the broader R&D Postdoc Program that focuses on training the next generation of industry scientists. An overwhelming majority of our postdocs go on to advance their careers in industry at leading pharma and biotech companies, including many at Amgen.

We are looking for talented, self-motivated individuals passionate about science and making high impact discoveries to work on Emerging Therapeutic Modalities. A major focus will be in the exciting area of Proximity Biology, including Targeted Protein Degradation, PROTACs and novel lysosomal degradation pathways. New postdoctoral fellows will take a multi-disciplinary approach combining chemical biology, molecular biology, proteomics, cell biology, and functional genomics to carry out these studies and develop novel technologies to modulate intractable targets.

  • Work collaboratively with leading scientists to make high impact discoveries that can change lives

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Postdoctoral Fellow we seek is a professional with these qualifications.

Basic Qualifications:

  • PhD at time of appointment

Preferred Qualifications:

  • PhD in biochemistry, molecular biology, cell biology, cancer biology, or pharmacology.

  • Broad knowledge of molecular and cellular biology with demonstrated independent research eminence through first author publications in top journals

  • Deep understanding of cellular protein degradation pathways (ubiquitin-proteasome system, endo-lysosome pathway), and/or experience in PROTACs or other related emerging technologies.

  • Research experience in molecular and cellular techniques, including quantitative cell-based assay development, cell line engineering, Genome-wide CRISPR screening, and confocal microscopy.

  • Excellent organizational, interpersonal and communication skills

  • A passion to explore the unknown and make discoveries that will chart new areas of biology

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) $$77,626 $86,250

Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans

  • Flexible work models, including remote and hybrid work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

You may visit the Post Doctoral Fellows Career Page for more information and opportunities.

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

Company

We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.

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Company info
Website
Phone
805-447-1000
Location
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
California
91320-1799
United States

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