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Sr. Associate Scientist, Antibody Discovery

Employer
Prellis Biologics, Inc.
Location
Berkeley, California
Salary
Up to $130,000 per year + benefits
Start date
Jan 13, 2025
View more categoriesView less categories
Discipline
Science/R&D
Required Education
Bachelors Degree
Position Type
Contract

Prellis Biologics uses proprietary technology to 3D print lymph node organoids, which we are using to generate in vitro human lymph node cocultures for generating antigen-specific B-cells.  We are seeking a Senior Associate Scientist, Antibody Discovery to join our Antibody Discovery team.  In this role you will be supporting high-throughput antibody discovery efforts, particularly using primary cell co-culture approaches.  The ideal candidate will have a strong background in molecular biology and cell culture work, with significant experience in supporting end-to-end antibody discovery campaigns.

Key Responsibilities:

  • Perform high-throughput cellular biology techniques, including but not limited to, cell culture, Flow Cytometry, Fluorescence-activated cell sorting (FACS), and ELISPOT.
  • Set up and maintain primary cell co-cultures using aseptic techniques. Develop, troubleshoot, and drive protocol optimization for enhanced efficiency and increased throughput.
  • Develop and optimize automation protocols for improved efficiency in molecular and cellular assays.
  • Collaborate with cross-functional teams in a fast-paced, matrixed environment. Maintain accurate records of experiments, analyze data independently, and present results in team meetin

Qualifications:

  • B.S in Molecular Biology, Immunology, Biotechnology, or related life science field with 4+ years of experience, or M.S. with 2+ years of relevant experience.
  • Strong proficiency in maintaining primary cell co-culture systems is required.
  • Proficiency in Flow Cytometry workflows and single cell sorting for sequencing.
  • Experience with FlowJo or comparable analysis software.
  • Have strong experience in single B-cell antibody discovery workflows with an end goal of identifying novel therapeutic candidates.
  • Have prior experience with operating SONY MA900 cell sorters and MACSQuant analyzers.
  • Thrive in collaborative environments and are open to a mentorship role within the team.
  • Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment.
  • Excellent communication skills and ability to document and present experimental results.

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