Sr. Associate Scientist, Antibody Discovery
- Employer
- Prellis Biologics, Inc.
- Location
- Berkeley, California
- Salary
- Up to $130,000 per year + benefits
- Start date
- Jan 13, 2025
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- Discipline
- Science/R&D
- Required Education
- Bachelors Degree
- Position Type
- Contract
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Prellis Biologics uses proprietary technology to 3D print lymph node organoids, which we are using to generate in vitro human lymph node cocultures for generating antigen-specific B-cells. We are seeking a Senior Associate Scientist, Antibody Discovery to join our Antibody Discovery team. In this role you will be supporting high-throughput antibody discovery efforts, particularly using primary cell co-culture approaches. The ideal candidate will have a strong background in molecular biology and cell culture work, with significant experience in supporting end-to-end antibody discovery campaigns.
Key Responsibilities:
- Perform high-throughput cellular biology techniques, including but not limited to, cell culture, Flow Cytometry, Fluorescence-activated cell sorting (FACS), and ELISPOT.
- Set up and maintain primary cell co-cultures using aseptic techniques. Develop, troubleshoot, and drive protocol optimization for enhanced efficiency and increased throughput.
- Develop and optimize automation protocols for improved efficiency in molecular and cellular assays.
- Collaborate with cross-functional teams in a fast-paced, matrixed environment. Maintain accurate records of experiments, analyze data independently, and present results in team meetin
Qualifications:
- B.S in Molecular Biology, Immunology, Biotechnology, or related life science field with 4+ years of experience, or M.S. with 2+ years of relevant experience.
- Strong proficiency in maintaining primary cell co-culture systems is required.
- Proficiency in Flow Cytometry workflows and single cell sorting for sequencing.
- Experience with FlowJo or comparable analysis software.
- Have strong experience in single B-cell antibody discovery workflows with an end goal of identifying novel therapeutic candidates.
- Have prior experience with operating SONY MA900 cell sorters and MACSQuant analyzers.
- Thrive in collaborative environments and are open to a mentorship role within the team.
- Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment.
- Excellent communication skills and ability to document and present experimental results.
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