Research Scientist, Liver Disease
- Employer
- Takeda
- Location
- Boston, Massachusetts
- Start date
- Nov 24, 2024
View more categoriesView less categories
- Discipline
- Regulatory, Science/R&D, Biotechnology, Pathology
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Genetown, Best Places to Work
Job Details
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Job DescriptionResearch Scientist, Liver Disease
About the role:
At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.
Join Takeda as a Research Scientist, Liver Disease Research where you will be part of a team focused on validation of novel targets and the evaluation of drug candidates for the treatment of chronic fibroinflammatory liver diseases.
How you will contribute:
- You will apply expertise in executing in vitro studies relevant to fibroinflammatory liver disease biology and pharmacology.
- You will play a central role in generating key data for evaluating potential targets, mechanism of action and/or drug candidate efficacy and pharmacodynamics.
- You will need to be a highly collaborative and energetic team player and a self-directed learner with a keen interest in focused, fast-paced research.
- Designs and executes relevant target and drug candidate validation studies using contemporary methods and tools.
- Using a broad range of technologies, determine mechanism of action for drug targets and candidates with appropriate controls
- Implement target-specific assays to assess target and drug activity in vitro and/or in vivo, as appropriate
- Identifies orthogonal applications of target, pathway, or platform biology in other fibroinflammatory diseases
- Participate on cross-functional teams and provide technical leadership in area of expertise; may lead an initiative or one of a broader scope with a less-defined outcome
- Prepare technical reports, summaries, protocols, and quantitative analyses in written and/or oral form
- Proactively identify complex obstacles to progress in specific areas; recommend and implement solutions using a diverse set of resources; regularly add value to research projects through creative ideas
- Manage a wide variety of tasks, techniques, and projects; integrate these responsibilities to produce quality result with a high level of efficiency; may act as a scientific mentor to others
- Keep an accurate, comprehensible, concise notebook in accordance with company policy
- Maintain lab equipment and supplies as needed
- Maintain a safe and organized lab bench
- Communicate with colleagues effectively
- Present data to other scientific staff or cross-functional project team; may present data/posters to external research or scientific community.
Minimum Requirements/Qualifications:
- PhD degree in a scientific discipline (or equivalent), or
MS with 6+ years relevant experience, or BS with 8+ years relevant experience in vitro drug discovery research
- Demonstrated ability to independently solve scientific problems using multiple, state-of-the-art technologies and approaches
- Significant experience with drug discovery applications of cell culture including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models, preferably models that recapitulate cellular cross-talk in fibroinflammatory or diseased tissues
- Expertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIP
- Experience and continued willingness to work with live rodents and animal tissue
- Demonstrates exceptional project management skills and in-depth in vitro cell and molecular biology assay experience
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Boston, MAU.S. Base Salary Range:
108,500.00 - 170,500.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull timeJob Exempt
YesCompany
For over 240 years, Takeda’s propensity to evolve has driven the next generation of innovation. Today, our organization spans the globe—colleagues across business units and functions face challenges head-on to deliver life-transforming treatments, guided by our commitment to patients, our people and the planet.
As a values-based, R&D-driven biopharmaceutical leader headquartered in Japan, we focus our R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. In addition to our R&D efforts, we’re laser-focused on harnessing the power of data, digital, and technology to improve health outcomes for patients across the globe.
Since our founding in Japan, integrity and putting patients first have been at the heart of our identity. We're proud of our employees and their commitment to improving the quality of life for patients, and to working with our partners in health care in approximately 80 countries and regions. With each new breakthrough comes opportunities to develop your career, hone new skills, and create a brighter future
For more information, visit https://jobs.takeda.com/
- Website
- https://www.takeda.com/
- Location
-
650 East Kendall Street
Cambridge
MA
02421
United States
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