Vice President - Research Biology

Job Type Full-time

  

What you should know about Anaptys:

Anaptys is an immunology-focused, clinical-stage biotechnology company with a 19-year track-record of discovering life-changing therapeutic antibodies. Over that time, we have worked to create a work environment where every role has meaning, every team member is respected and every day is a chance to make a difference for people living with autoimmune and inflammatory diseases. 

Our portfolio today includes two checkpoint agonists: ANB032, our BTLA agonist, in a Phase 2b trial for the treatment of atopic dermatitis and rosnilimab, our PD-1 agonist, in a Phase 2b trial for the treatment of rheumatoid arthritis and in a Phase 2 trial for the treatment of ulcerative colitis. We also have other immune cell modulator candidates in our portfolio, including ANB033, an anti-CD122 antagonist antibody, entering a Phase 1 trial and ANB101, a BDCA2 modulator antibody, in preclinical development.

Our success is rooted in the diversity of our teams’ experience, knowledge and background. We’re doers, thinkers and collaborators who embrace and live by our values: accountability, transparency and humility.

Here’s What You Will Do:

Essential Functions You Will Be Responsible For:

· Directs the activities of scientists in the discovery and optimization of therapeutic antibodies in the field of inflammation and autoimmune disease.

· Demonstrated success and major contributions to research programs that have transitioned milestones into clinical development (project leadership role, IND, IB, regulatory guidance, conflict management, presentations to governance bodies including BoD and external SABs).

· Provides guidance and strategic oversite for mechanism of action studies to support all programs across the Anapyts’ portfolio.

· Provides guidance and strategic oversite of comparative pharmacology experiments in normal and diseased patient samples to benchmark internal assets and support indication selection decisions.

· Provides guidance and strategic oversite to molecular biology work.

· Develops and successfully coordinates strategies to ensure effective achievement of project and company goals.

· Provides immunology support to multidisciplinary project teams and participates in strategies for generating clinical candidates.

· Initiates projects and/or leads therapeutic antibody discovery project teams, including designing key strategies and interpreting results to further project objectives, working effectively across disciplines to accomplish project goals.

· Ensures scientific excellence within cell biology and across research programs.

· Regularly reviews and interprets research data, monitors and evaluates scientific progress.

· Maintains broad scientific and technical knowledge within disciplines relevant to Anaptys’ portfolio and in-depth knowledge relevant to specific Research projects.

· Presents research findings and conclusions clearly and effectively to senior management, scientific advisory panels, and at external meetings, as appropriate.

Supervisory Responsibilities You Will Have

· Hire, lead, and develop Team of 12 - 18.

Requirements

  

Here’s What You Will Bring to Anaptys:

Education & Experience: 

· PhD plus 12 years post-doctoral experience in Immunology, Cell Biology, Biomedical Sciences, or a related field with 8 years productive experience in the biotechnology or pharmaceutical industry in biologics drug discovery.

· Demonstrated success in project leadership, independent and innovative scientific thinking and experimental design/approaches.

· At least five years’ experience managing and leading a group of biologists in a matrixed project team environment.

· Strong scientific publication and external presentation record in accord with years of experience.

· Experience working on a project that has transitioned into clinical development successfully.

Knowledge and Competencies: 

· Strong working knowledge of cellular immunology and molecular biology, including autoimmune and inflammatory diseases, with an applied understanding of antibodies, antibody generation, optimization and characterization, and broad biologics drug discovery research.

· Demonstrated success in drug discovery project leadership, independent and innovative scientific thinking and experimental design/approaches.

· Knowledgeable in flow cytometry approaches.

What’s Included in Your Compensation and Benefits Package:

Our generous benefits package is industry leading. Beyond base salary and a target bonus, we offer stock options, RSUs and a 10% 401k match to help you secure your financial future. Our robust time off policy provides employees a unique holiday schedule that incorporates long weekends throughout the year, in addition to the yearend company closing and additional vacation time.

Of course we round out our benefits with company sponsored dental, vision and life insurance plans. Our medical plans are benchmarked and are considered extremely competitive.

The salary range for this position is $280,301 - $360,887 with an 30% bonus target. Anaptys considers a variety of factors when determining base compensation, including experience and qualifications. These considerations mean actual compensation will vary 

What Else You Should Know:

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit and talk or hear. The employee frequently is required to use hands to finger, handle or feel. The employee is occasionally required to stand, walk and reach with hands and arms. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision and ability to adjust focus in order to read.

Work Environment

The work environment characteristics are representative of those an employee encounters while performing the essential functions of this job, typically in an open office environment. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

The noise level in the work environment is usually moderate.

May be required to travel by plane or car.

This position requires working with biological and/or chemical hazards.

All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.

Salary Description $280k - 360k, 30% bonus, 10% 401k, Options & RSU