Principal Scientist Computational Chemistry Amgen San Francisco
- Employer
- Amgen
- Location
- South San Francisco, California
- Start date
- Nov 7, 2024
View more categoriesView less categories
- Discipline
- Science/R&D, Biotechnology, Chemistry
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Biotech Bay, Best Places to Work
Job Details
At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.
Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Principal Scientist - Computational Chemistry - Amgen San FranciscoWhat you will doLets do this. Lets change the world. We are actively seeking a highly qualified and motivated Principal Scientist to join the Computational Chemistry team within Amgens Center for Research Acceleration and Digital Innovation (CRADI). CRADI functions within our drug discovery engine to accelerate our pipeline from target inception through drug development. As part of the Computational Chemistry team, you will develop and apply tools to generate novel molecules and predict chemical properties to guide the successful discovery of small molecule therapeutics. This position is the first Computational Chemistry role in our Amgen San Fransisco site. In this vital role you will:
Participate on multiple interdisciplinary discovery project teams and play a key role in defining project strategies and achieving project milestone transitions
Apply structure-based, ligand-based and machine learning/generative design to advance drug discovery projects (both small molecule and targeted protein degradation projects)
Analyze potential drug targets to assess their druggability and help identify best modality and contribute to develop the screening strategy
Perform virtual screening campaigns to identify novel starting points
Guide and apply new Machine Learning and Artificial Intelligence technology developments
Guide and apply new protein degradation workflows working closely with Induced Proximity Platform colleagues
Contribute to guide infrastructure improvements, software portfolio recommendations and prospecting of relevant cutting-edge computational technologies/companies
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications.
Basic Qualifications:
Ph.D. degree and 2 years of experience in computational chemistry
Or
Masters degree and 5 years of experience in computational chemistry
Or
Bachelors degree and 7 years of experience in computational chemistry
Preferred Qualifications:
PhD. in Computational Chemistry or related field
Proven accomplishments supporting drug design projects with 4+ years of relevant experience in the biopharmaceutical industry
Expert in the field of computational chemistry in an industry setting and good knowledge of related and adjacent disciplinary areas
Thorough understanding of the drug discovery process from lead screening to late-stage optimization and know how to maximize the impact of computational modeling
Good external publication record, excellent communication and organizational skills and demonstrated ability as a team leader
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is $163,479 - $199,808 Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.comIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Company
We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.
We live the mission.
We win together.
We thrive on continual challenge.
Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.
At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.
Connect with us to explore how you can Win, Live, and Thrive at Amgen.
- Website
- http://careers.amgen.com/
- Phone
- 805-447-1000
- Location
-
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
California
91320-1799
United States
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