Research Sr. Scientist, Inflammation (GI2) Drug Discovery

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At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

About the Role:

The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, andinflammatory diseases. We seek skilled bench scientists to join our cross-functional discovery teams.

• Generate and execute preclinical development strategies to support candidate selection and mechanistic characterization, facilitating efficient clinical validation of impactful medicines for patients with inflammatory and autoimmune disorders
• Apply deep scientific expertise in immunology and/or cell biology to creatively mature innovative novel concepts within our team, in matrixed collaboration with other Takeda scientists, and external partners.
• Drive an inclusive, open, and effective culture in a fast-growing drug discovery group.

Accountabilities:

• Generate data packages supporting candidate selection and asset characterization based on subject matter expertise, technical literature, and awareness of current industry standards.
• Champion scientific integrity and rigor in data analysis, preparation, and interpretation of detailed protocols/SOPs.
• Collaborate productively within a matrixed structure, and clearly communicate results, challenges, and impact in presentations and conversations with broad audiences. Integrate data generated from other disciplines.
• Critically assess and identify vendors and appropriate contract research organizations to supplement internal nonclinical studies.
• Think independently and creatively about novel therapies for patients suffering from immune-driven disorders.

Education & Competencies (Technical and Behavioral):

• PhD degree with 2+ years industry experience, or MS with 8+ years’ experience, or BS with 10+ years’ experience.
• Adept at isolation and running in vitro assays with cell lines and primary human immune cells.
• Expertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIP.
• Experience developing and/or evaluating novel small molecule, biologic and/or nucleic acid therapeutics.

• Demonstrates strong organizational and project management skills and effective written and verbal communication skills.

This position is currently classified as “onsite” in Cambridge, MA.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

U.S. Base Salary Range:

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Job Exempt