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Executive Director and Head of Structural Biology

Employer
Takeda
Location
Boston, Massachusetts
Start date
Sep 27, 2024
View more categoriesView less categories
Discipline
Science/R&D, Biology
Required Education
Doctorate/PHD/MD
Position Type
Full time
Hotbed
Genetown, Best Places to Work

Job Details

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’sPrivacy Noticeand Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Objective / Purpose:

Takeda is looking for a well-established transformative leader in the field of structural Biology to build and lead a state of art, future focused structural biology organization to support Takeda’s pipeline in three therapeutic areas of interest: Oncology, Gastroenterology & Immunology, and Neuroscience. The structural biology group will support drug discovery encompassing three core modalities in small molecule, biologics and cell therapies. The successful candidate will lead a team responsible for all structural studies at Takeda involving X-Ray crystallography, Cryo Electron Microscopy, structural modeling and AI driven approaches. Proven track record of team building and leadership along with in depth knowledge of the structural biology field is essential for this role.Accountabilities: Scientific Leadership:
  • Build, lead and manage a team of structural biologists, protein scientists, and computational modeling experts.
  • Drive scientific excellence in protein structure determination, molecular modeling, and drug-target interaction validation.
  • Collaborate with cross-functional teams (including teams in Global Biologics, Global Chemistry, therapeutic areas, and preclinical development) to advance drug discovery projects.
Protein Structure Determination:
  • Oversee the design, execution, and interpretation of structural biology experiments (X-ray crystallography, cryo-EM, etc.).
  • Ensure high-quality protein production for structural studies.
  • Apply cutting-edge techniques to elucidate protein-ligand interactions and conformational dynamics.
Computational Modeling:
  • Work closely with computational scientists to develop and apply molecular modeling approaches.
  • Utilize structural information to guide drug design and optimization.
Collaboration and Communication:
  • Collaborate extensively with internal Takeda stakeholders
  • Collaborate with external academic institutions, CROs, and research partners.
  • Present findings at scientific conferences and contribute to publications.
Strategic Planning:
  • Define the strategic direction for the Structural Biology department.
  • Align research goals with corporate objectives and therapeutic areas of interest.
Mentoring: Mentor and develop future leaders, junior scientists, fostering a culture of innovation, collaboration, and scientific excellence.Program leadership: Experience in leading discovery programs to development with be desirable

Education & Competencies (Technical and Behavioral): Ph.D. in Structural Biology, Biochemistry, or related field. 15+ yearsof relevant experience in pharmaceutical or biotechnology industry. Proven track record of building and leading successful structural biology teams . Track record of supporting biologics, as well as small molecule programs. Deep and diverse knowledge in multiple areas of structural biology including X-Ray crystallography, CryoEM, computational antibody, protein – ligand modeling and protein chemistry.Excellent leadership, communication, and interpersonal skills, with the ability to lead a teams, projects and collaborate effectively across disciplines.Demonstrate enterprise leadership with an ability to influence without authority.

Established leader in the field as demonstrated by publications and conference presentations

Well versed on emerging technologies including realistic implementation of AI/MLThis position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$205,100.00 - $322,300.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Company

For over 240 years, Takeda’s propensity to evolve has driven the next generation of innovation. Today, our organization spans the globe—colleagues across business units and functions face challenges head-on to deliver life-transforming treatments, guided by our commitment to patients, our people and the planet.

As a values-based, R&D-driven biopharmaceutical leader headquartered in Japan, we focus our R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. In addition to our R&D efforts, we’re laser-focused on harnessing the power of data, digital, and technology to improve health outcomes for patients across the globe.

 

Since our founding in Japan, integrity and putting patients first have been at the heart of our identity. We're proud of our employees and their commitment to improving the quality of life for patients, and to working with our partners in health care in approximately 80 countries and regions. With each new breakthrough comes opportunities to develop your career, hone new skills, and create a brighter future

For more information, visit https://jobs.takeda.com/

Company info
Website
Location
650 East Kendall Street
Cambridge
MA
02421
United States

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