Research Associate II, Single Cell and Spatial Transcriptomics with Childhood Cancer Data

Research Associate II, Single Cell and Spatial Transcriptomics with Childhood Cancer Data Initiative

Job ID: req4016
Employee Type: exempt full-time
Division: Cancer Research Technology Program
Facility: NIH
Location: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

 PROGRAM DESCRIPTION         

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR), where CRTP scientists work collaboratively with intramural NCI investigators to provide research technologies and expertise.

KEY ROLES/RESPONSIBILITIES

We are seeking a highly motivated Research Associate to provide dedicated single cell and spatial research support for the intramural Childhood Cancer Data Initiative (CCDI) effort. This will include close collaboration with CCDI Investigators to generate high-quality datasets for multiple projects using established single cell methods and help validate and employ emerging technologies. A major goal of this Initiative is to establish tumor cell atlases for rare pediatric malignancies.

This Research Associate will have a role in:

• Providing state-of-the-art single cell and spatial research support to CCDI Investigators
• Performing single cell captures, library preparation, quality control and sequencing
• Processing tissue sections for Spatial Transcriptomics
• Helping with experimental design, sample preparation and project troubleshooting
• Working to implement support for advanced single cell and spatial methods more efficiently and effectively

**THIS POSITION IS CONTINGENT UPON FUNDING APPROVAL** 

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency.
• In addition to the education requirements, a minimum of five (5) years of related experience is required
• Experience performing cell and molecular biology experiments
• Familiarity with next generation sequencing methods
• Must have excellent written and verbal communication skills
• Must be detail-oriented, and able to manage multiple projects simultaneously
• Must be able to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS 

Candidates with these desired skills will be given preferential consideration:

• Experience with NextGen library generation, DNA/RNA isolation, and DNA/RNA quantitation
• Experience in Single Cell captures and library preparation
• General cell biology experience, including handling live cells and counting
• Experience working in a core facility or other team-based environment
• Demonstrated ability to learn new technologies quickly
• Knowledge and background experience in cancer biology and immunology

JOB HAZARDS

• This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s)
• This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations.

Commitment to Diversity
All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.

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