Associate Scientist, Cell Therapy

Why Join Intellia?

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.

We wantall ofour people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.

Associate Scientist

Autoimmune Cell Therapy

Why JoinIntellia?

Our mission is to developcurativegenome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.

We wantall ofour people to go beyond what is possible. Wearen’tconstrained by typical end rails, and wearen’tout to just “treat” people.We’reall in this for something more.We’redriven to cure and motivated for change. Just imagine the possibilities of what we can do together.

How you will Achieve More with Intellia:

We are excited to welcome a new Associate Scientist to our Cell Therapy group at Intellia, where we leverage CRISPR technology to fully unleash the power of cell-based therapies for autoimmune diseases. In your new role, you will engineer CAR-targeted mouse and human T cells, including regulatory T cells, to further characterize them phenotypically via flow cytometry and in various in vitro assays (activation, cytotoxicity, cytokine production, proliferation, suppressive activity) as well as for in vivo safety, efficacy, and persistence.

Additional role responsibilities include:

● T cell engineering and production using CRISPR/Cas9 technology.

● Performing multicolor flow cytometry analysis.

● Assess T cell cytokine profiles by ELISA or MSD.

● Coordinate and collaborate with colleagues to assess CAR-T cell functionality and safety in vitro and vivo.

● Collaborate in conducting animal studies (mouse handling, injections, cell trafficking via IVIS, tissue collection, endpoint analyses).

● Key contributor to study designs, data analysis and presentations

About You:

Our ideal candidate will have a solid background in immunology, especially T cell and CAR-T cell biology, and seeks to lead innovative, cutting-edge studies in an enthusiastic and collaborative environment. If you describe yourself as a great team player who wants to be challenged, have fun, grow with us, and looks for opportunities to break new ground, we encourage you to apply!

Additional role requirements include:

● B.S. or M.S. in immunology with 5+ years of experience in industry or academic lab.

● Strong organizational and data documentation skills.

● Ability to implement, optimize and/or troubleshoot protocols and operating procedures.

● Comfortable working in a team setting and collaborating within a group.

Meet your future team:

The Autoimmune Cell Therapy Team at Intellia is an energetic, highly motivated, and fun group of scientists. Teamwork makes the dreamwork is our mantra and we strongly support each other with all individual projects. We are dedicated to making a difference for autoimmune patients by developing an unprecedented, CRISPR-based approach to generate highly potent synthetic Tregs and other cell-based therapeutic approaches, and direct them to sites of inflammation. Your future hiring manager is the Group Leader of the Autoimmune Cell Therapy Team.

All team members are currently working onsite in a wet-lab environment. Therefore, you are required to be local to the greater Boston/Cambridge area, or open to relocating. While much of the day-to-day tasks require wet-lab work, our team aims to build not just technical expertise but to promote an environment for scientific and personal development and career growth in biotech. If you decide to join us, you can expect to become a highly valued member of a hardworking and collaborative team. We look forward to fostering your skills, learning from your experiences, and building a larger team together to impact patients’ lives.

Covid-19 Vaccination Policy:All Intellia employees, regardless of work location, are expected to follow all applicable federal, state, and local public health regulations and guidelines, and are strongly encouraged to follow all public health recommendations, including being vaccinated for COVID-19.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.