Research Associate II/Senior Research Associate I, Cell Biology (Contract)

Who We Are:

ReCode Therapeutics is a clinical-stage genetic medicines company using precision delivery to power the next wave of mRNA and gene correction therapeutics. ReCode’s proprietary Selective Organ Targeting (SORT) lipid nanoparticle (LNP) platform enables highly precise and targeted delivery of genetic medicines directly to the organs, tissues and cells implicated in disease, enabling improved efficacy and potency. ReCode’s lead programs include RCT1100 for the treatment of primary ciliary dyskinesia caused by pathogenic mutations in the DNAI1 gene, and RCT2100 for the treatment of the 10-13% of cystic fibrosis patients who have Class I mutations in the CFTR gene and do not respond to currently approved CFTR modulators. RCT1100 and RCT2100 are inhaled disease-modifying mRNA-based therapies formulated using the SORT LNP delivery platform. ReCode is expanding its pipeline to develop potential therapies for other rare and common genetic diseases, including musculoskeletal, central nervous system, liver and infectious disease indications.

Summary of Position:

We are seeking a highly motivated individual to join the Recode Biology team in Durham, NC. In this role, you will be responsible for establishing and maintaining cell cultures (primary mammalian cells) to support the maintenance and screening of LNPs. You will gain hands on training in developing cell delivery methods including aerosol delivery to cells as well as developing cell-based and biochemical assays. You will collaborate with an inter-disciplinary team of ReCode scientists and will have access to excellent experimental and analytical facilities. This is a contract position with expectations to be 100% time on site in Durham, NC.

Responsibilities:

• Cell culture, maintenance and QC of primary cells and cell lines.
• Prepare aliquots of media, PBS, antibodies, supplements, and inventory management.
• Coordinate with fellow researchers within the team to plan for cell culture requirements.
• Assist and perform downstream Molecular Biology assays.
• Plan and perform experiments and analyze data with supervision.
• Maintain thorough and detailed electronic lab notebooks and documentation records
• Present data at group meetings.
• Contribute to lab management activities.

Qualifications:

• Bachelor’s or Master’s degree in biology or related field.
• 4+ years of hands-on experience in the biopharma industry.
• Demonstrated high level expertise and proficiency in primary human or mouse cell culture
• Experience with cell culture and differentiation of stem cells.
• Laboratory experience with a variety of techniques in Cell Biology, Molecular Biology and Biochemistry such as mammalian cell culture, toxicity/viability assays, protein extraction, Western blot, DNA/RNA purification and analysis.
• Hands-on experience with microscopy and immunofluorescence is a plus.
• Solid organizational skills including attention to details, multi-tasking skills to facilitate data analysis and troubleshooting.
• Demonstrated ability and passion for working in a fast paced, multidisciplinary small team environment.

Salary Range: $40-$45/hr

Benefits Offered for Full-Time Employees: 

• No premium cost for employees - 100% subsidized by ReCode for full-time employees
• Company 401k contribution
• 15 days of company paid holidays, including a holiday shutdown (usually the last week of the year)
• Mental health support for employees & their families
• FSA available, including a lifestyle spending account subsidized by company
• Employee discounts at hotspots

ReCode Therapeutics (www.recodetx.com) offers a competitive compensation/benefits package with a friendly, collaborative culture that values employee engagement and ongoing career development.

ReCode Therapeutics is an Equal Opportunity Employer.