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Director, SEC Reporting and SOX

Employer
4D Molecular Therapeutics
Location
Emeryville, California
Start date
Aug 26, 2024
View more categoriesView less categories
Discipline
Administration, Finance
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay, Best Places to Work

Job Details

Attention recruitment agencies: All agency inquiries are vetted through 4DMT’s internal Talent Acquisition team. No unsolicited resumes will be accepted. The 4DMT Talent Acquisition team must expressly engage agencies on any requisition. Agencies contacting hiring managers directly will not be tolerated, and doing so may impact your ability to work with 4DMT in the future.

 

4DMT is a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines. We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products. We believe key features of our targeted and evolved vectors will help us create targeted product candidates with improved therapeutic profiles. These profiles will allow us to treat a broad range of large market diseases, unlike most current genetic medicines that generally focus on rare or small market diseases.  

Company Differentiators: 

•    Fully integrated clinical-phase company with internal manufacturing
•    Demonstrated ability to move rapidly from idea to IND
•    Five candidate products in the clinic and two declared pre-clinical programs
•    Robust technology and IP foundation, including our TVE and manufacturing platforms
•    Initial product safety and efficacy data substantiates the value of our platforms
•    Opportunities to expand to other indications and modalities within genetic medicine

The Director of SEC Reporting and SOX will lead the SEC reporting and the SOX program. This is a highly visible role that offers the opportunity to work with various Finance functions within the Company, including Accounting, FP&A, Investor Relations, Treasury, Stock Administration, and Corporate Tax, as well as HR, Legal, and various operational functions, which will allow you to gain a strong understanding of the Company’s business and operations. 

The ideal candidate has strong knowledge of US GAAP and SOX 404 compliance requirements and experience in the biotech/pharma industry

RESPONSIBILITIES:  

  • Manage the SEC financial reporting process, including the preparation of the Company’s SEC filings (including Forms 10-K, 10-Q, 8-K, and various other filings), working closely with other functions as needed and ensuring accurate and timely submissions to regulatory authorities
  • Prepare financial statements (including a statement of cash flows), EPS calculation, footnotes, MD&A, accounting memos, US GAAP Disclosure Checklist, and disclosure support
  • Proactively research industry reporting trends and perform benchmarking to make recommendations to improve and strengthen the Company’s SEC filings
  • Manage accounting for stock-based compensation in compliance with ASC 718, including valuation assumptions and preparation of journal entry
  • Coordinate with Legal, Finance, Investor Relations, and other teams with the Company to prepare SEC Filings and lead Disclosure committee meetings
  • Manage SOX program in collaboration with the Company’s third-party service provider, including risk assessment, design assessment, walkthroughs, documentation, testing of internal controls and ITGCs in FloQast
  • Work in partnership with control owners and business leaders across the Company to identify, develop, recommend, and implement appropriate control changes that may result from business changes, non-routine transactions, or system implementations
  • Monitor management’s remediation efforts to closure, including review of supporting evidence
  • Act as the primary point of contact for internal and external auditors during the audit process, providing support and documentation as required for assigned areas
  • Other projects and responsibilities may be added at the manager’s discretion
  • Manage workload distribution, prioritize tasks, and ensure deadlines are met effectively.

QUALIFICATIONS: 

Education: 

  • Bachelor’s degree in Accounting or related field
  • CPA

Experience: 

  • 12 + years of relevant experience with a mix of Big 4 public accounting and a compliance role in the biotech industry

Skills: 

  • Advanced understanding of SEC Reporting and SOX 404
  • Excellent Excel spreadsheet skills and proficiency with other Microsoft Office products (Word, PowerPoint, etc.)
  • Hands-on experience with SEC filing systems such as Active Disclosure
  • Strong analytical and problem-solving skills, with the ability to interpret complex financial data and trends
  • Excellent communication and interpersonal skills, with the ability to collaborate effectively across functional teams
  • Strong attention to detail, decision-making, problem-solving, project management, and organizational skills
  • Ability to quickly learn and utilize reporting and other management systems and tools.

Base salary compensation range $218,000 - $238,000

Please note: the base salary compensation range and actual salary offered to the final candidate depends on various factors: relevant work experience, skills, and years of experience

 

4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran, and any other category protected under applicable federal, state, provincial and local laws.   Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

Company

4DMT is a gene therapy company with a transformative discovery platform --Therapeutic Vector Evolution --that enables our “disease first” approach to product discovery and development, thereby allowing us to customize our AAV vectors to target specific tissue types associated with the underlying disease.


At 4DMT we are creating and developing optimized “biopharmaceutical grade” AAV vectors that will allow us uniquely to unlock the full potential of gene therapy. Our customized and proprietary AAV vectors are each designed, according to a 4DMT Target Vector Profile, to deliver genes to specific cells and tissues in the body to eradicate both rare and large market diseases.


While AAV gene therapy pioneers are making great strides with the first wave of products, hurdles still exist with the use of conventional vectors. The most commonly used AAV capsids (e.g., AAV2, 5, 8 and 9) were identified either 1) as contaminants in lab stocks of adenovirus, or 2) through monkey tissue processing. Therefore, these conventional vectors are not targeted specifically to any tissue in the body. This can lead to inefficient and non-specific delivery, thus requiring extremely high doses and potentially resulting in toxicities (including inflammation), high manufacturing burdens and suboptimal efficacy. In addition, suboptimal routes of delivery can be required for delivery to the right tissues (e.g., subretinal delivery to the retina). Finally, pre-existing neutralizing antibodies in many patients can limit efficacy, clinical trial enrollment and market sizes. 4DMT Innovation empowers us to create new and improved next generation AAV capsids to allow targeted delivery of our products by the optimal clinical route of administration.


At 4DMT we use our robust discovery platform, termed “Therapeutic Vector Evolution,” to create customized and proprietary gene delivery vehicles (novel AAV vectors) to deliver genes to specific tissues and cells in the body by the optimal route of administration. We use the power of evolution to create and refine these optimized vectors through genetic diversification and then natural selection in vivo.


4D Purpose Statement:  Boldly Innovating to Unlock the Full Potential of Gene Therapy for Countless Patients


GUIDING PRINCIPLES

 

  • Dare to Cure - Patients are waiting. Create big dreams for patients and take calculated risks to achieve them
  • Break Boundaries - Question the status quo and innovate beyond conventional approaches
  • Beyond Yourself - It's about patients, their families, our team, our families. We strengthen each other.
  • Prepare and Execute Relentlessly - Start with the end in mind, over-prepare and make contingency plans to your contingency plans


We invite all of you who share our passion and vision in creating the ultimate gene therapy products to cure genetic and rare diseases in children and adults. We seek the best people in the industry who identify with our mission and innovative results-driven approach. We offer an inspiring and collaborative environment that encourages individual contributions, recognizes performance in multiple ways, offers generous benefits and provides challenging opportunities for career development. 
 

Company info
Website
Phone
510-505-2680
Location
5858 Horton St. Suite 455
Emeryville
California
94608
United States

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