Global Medical Director, Neuromuscular Franchise Lead

Job Title:

Global Medical Director, Neuromuscular Franchise Lead

Location:

Remote

Position type:

FLSA:

Full time

Exempt

Department:

Medical Affairs

Strive to Bring a Profound Difference to our PatientsAt Avidity Biosciences, we are passionate about the impact of every employee in realizing our vision of improving people’s lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed, solution-oriented thinker, join us in making a difference and become part of our growing culture that is integrated, collaborative, agile and focused on the needs of patients. Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs™). Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline, including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline, and people, please visit www.aviditybiosciences.com and engage with us on LinkedIn and Twitter.The OpportunityAvidity Biosciences is searching for a highly motivated and experienced individual for the position of Global Medical Director, Neuromuscular Franchise to build and lead our neuromuscular global medical director team.  This individual will develop and implement the strategic/tactical medical plan for each of our 3 neuromuscular programs.  In addition, this role will lead the build out the broader global medical director team.   This role will be responsible for leading evidence generation efforts (Registry and IIS) required to meet unmet needs and inform physicians and patients of real world evidence as well as deliver foundational materials, training, and programs to move the scientific understanding of our 3 lead developmental compounds forward.   Cross functional partnerships across the organization will be key.  This will include clinical development, medical communications, regulatory, operations, program management, and marketing with goal of providing medical leadership in delivering therapeutic initiatives in FSHD, DM1, and DMD.  This position will also be a key member of the cross functional program teams. What You Will Contribute

• Fosters collaboration with Senior Leadership to inform and understand corporate strategy and ensure alignment of North America Medical Affairs strategic plan.
• Develop and build a fully integrated global medical director team across the neuromuscular programs
• Develop an integrated global medical affairs strategy to drive tactical planning across medical affairs
• Include in this integrated strategy key elements that will be critical for Medical Affairs success across regions that will ensure alignment with collaborative regional and therapeutic area plans.
• Responsibility for acting as medical affairs lead for one or more programs as required
• Lead and facilitate Ph 4 and real world evidence generation efforts
• Member of MRC and PMRC-working with internal stakeholders at the initiation, creation and review of educational and promotional materials. Provide medical expertise in review and approval of external resources, communication and publications to ensure medical accuracy, objectivity and fair-balance.
• Work closely with clinical trial teams to support clinical trial site recruitment and patient enrollment.
• Key member of cross functional neuromuscular programs team(s)
• Plan and execute strategic working group sessions and advisory boards with healthcare providers to collect needed clinical insights to inform medical strategy and tactics.
• Work with clinical development and HEOR teams to support inclusion of appropriate trial endpoints and outcome measures to inform physicians and payers.
• Develop foundational materials and support training for regional and medical field teams
• Collaborate with the Preclinical, Clinical Development, and Medical Affairs teams to translate clinical insights and data gaps into medical strategy
• Ensure alignment of the Medical Affairs activities and tactics with the launch readiness and program management plans and objectives.
• Provide medical expertise in support of developing content (slides, websites, standard response letters) for medical communications and education to advance disease state and clinical understanding
• Manage and regularly meet with a thought leader network to support the successful execution of Medical Affairs tactics.
• Represent Avidity at various scientific and clinical congress meetings.
• Play a lead role in providing strategic medical/scientific direction across the company portfolio.
• In collaboration with the program teams and publications lead, support development of global publication plan, and contribute to the development of key publications (abstracts, manuscripts, posters, presentations, etc.).
• Collaborate with thought leaders to develop clinical therapeutic concepts, identify messages for scientific communications based on preclinical or clinical data, and gain feedback on strategies to support medical affairs plan for pre-launch and marketed products.
• Collaborate with Legal/Compliance and Regulatory affairs and ensure understanding and adherence

to external policies and regulations.

• Be a key medical support point of contact for major commercial activities in area of responsibility
• Demonstrate and apply a deep understanding of government and industry guidelines, regulations, laws, etc., for appropriate scientific/medical exchange and communication with customers.
• Demonstrate, and lead by example, compliant behavior in all aspects of company work.
• Perform all duties in full compliance with company policies and governing law.
• Enhances organizational collaboration by encouraging dialog amongst team members to address issues, actively seeks solutions that improve the organization at the regional and national level.
• Maintains a positive attitude, anticipates and proactively adapts actions to seize opportunities during times of rapid change and/or uncertainly. Helps others during change through positive, solution-oriented approach

What We Seek

• PharmD/PhD/MD with experience leading and building medical affairs strategy including 10+ years of industry experience including building and leading highly functioning teams
•  Significant experience launching products including pre-launch prep.
• Experience in rare disease or specialty indications required.
• Flexible, entrepreneurial by nature, a collaborative team player who works well with patients, physicians, providers, payers, regulators, scientists, and peers.
• Must possess excellent communication skills, including ability to strategically synthesize and simplify complicated scientific topics into understandable messages for broad audiences.
• Leadership and influence skills, including a passion for working within multiple teams and proven ability to achieve results in a matrix organization.
• Must be able to actively manage and track many complex projects in parallel, structuring the actions of many people toward shared outcomes.
• Highly motivated, decisive, and results-oriented individual with the flexibility and creativity to excel in a rapidly growing and changing environment.
• Experience working with all levels of management and consulting with key business stakeholders. An ability to positively influence stakeholders in a team environment for greater outcomes.
• Strong team player that has a customer service approach and is solution oriented.
• Attention to detail and the ability to work individually, within a multi-disciplinary team, as well as with external partners and vendors.
• Embrace Avidity’s core values
• Ability to work independently and collaboratively, as required, in a fast-paced start-up environment consisting of internal and external team members.
• Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
• Proven track record of excellent communication and collaboration skills, including recognition by cross-functional partners; works well independently while exhibiting professional maturity, confidence, and competence
• Outstanding business acumen; knows the industry, Avidity’s value proposition, key competitors, and other marketplace factors/dynamics
• Agility and flexibility in a fast paced environment
• Ability to travel extensively and must possess a valid driver’s license. Weekend travel may be required

What We will Provide to You:

• The base salary range for this role is $273,600-$302,400. The final compensation will be commensurate with such factors as relevant experience, skillset, internal equity and market factors.
• Avidity offers competitive compensation and benefits which includes the opportunity for annual and spot bonuses, stock options and RSUs, as well as a 401(k) with an employer match. In addition, the comprehensive wellness program includes coverage for medical, dental, vision, and LTD, and four weeks of time off.
• A commitment to learning and development which includes a variety of programming internally developed by and for Avidity employees, opportunities for job-specific training offered by industry, and an education reimbursement program.

Avidity Biosciences

10578 Science Center Dr. Suite 125

San Diego, CA

92121

O: 858-401-7900

F: 858-401-7901