Senior Associate Scientist, Preclinical Development

The Role:

We are looking for an experienced preclinical scientist with a strong background in murine CNS administration procedures to help expand our therapeutic capabilities. We are seeking curious, enthusiastic, competent, and self-motivated individuals to work in our company. A willingness to embrace our cultural values will be critical for success in this role. This is an exciting opportunity to continue to build a successful therapeutics company from an early stage.

Here’s What You’ll Do:

• Assist with study design, protocol preparation, study execution (administration), in-life oversight, data collection, and report writing
• Perform and support rodent study procedures in accordance with the IACUC, including administration of our novel nuclease via CNS routes, complete health observations, sample collections, and necropsies

• Perform wet bench assays taking in vivo samples all the way through editing outcomes
• Perform histological protocol development, sample preparation, and data collection to support programs

• Maintain accurate and timely note keeping in our ELN system
• Collaborate with multiple scientists across the preclinical group and company
• Practice regulatory ready research while embracing the 3Rs (refine, replace and reduce)

Requirements:

• Bachelor’s degree with at least 3 years of experience or Masters degree in biological sciences with at least 2 years of experience or a closely related field
• Must be able to follow Institutional Animal Care and Use Committee approved protocols
• Demonstrated proficiency with CNS routes of injection (e.g. ICV, intraparenchymal), with experience in systematic injection routes a plus.
• Demonstrated competency in CNS sample collection
• Preferred experience in histology experimental methods (e.g. Cryostat, paraffin section, immunochemistry staining)
• Demonstrated ability to collaborate in a team-oriented environment
• Demonstrated ability in research data organization
• Exceptional verbal and written communication skills

Why join Life Edit and the ElevateBio ecosystem?

Life Edit Therapeutics is an integrated subsidiary of ElevateBio, a technology-driven cell and gene therapy company that is accelerating access to the cutting-edge technologies and expertise that can change the future of medicine. Our integrated model combines multiple R&D technology platforms – including Life Edit gene editing – and cGMP manufacturing to power the discovery and development of advanced therapeutics. Our ecosystem is designed to enhance speed, delivery, and probability of success to change patient lives.

Life Edit is an integral part of ElevateBio’s ecosystem of platform technologies and is pioneering focused next-generation gene editing technologies and therapeutics. Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA. Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies. We are looking for a unique individual who can continue to lead the cultural development of Life Edit and build on its momentum as an integral part of the ElevateBio ecosystem.

Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.

Our Vision:
We seek to be the world’s most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.

ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.