Principal Scientist, Discovery Immunology

(San Diego, CA)

Mirador is a next-generation precision medicine company focused on immunology and inflammation. The company’s Mirador360 ^TM precision development engine leverages the latest advances in human genetics and cutting-edge data science to rapidly advance new precision medicines for patients living with chronic immune-mediated inflammatory and fibrotic diseases. Launched in 2024, Mirador has raised over $400 million from leading life sciences investors and is based in San Diego, CA.

Summary

We seek a motivated, detail-oriented Principal Scientist, Discovery Immunology with strong background in immunology / cell biology and experience developing cell-based assays to support our efforts in target validation, early phase antibody drug discovery, IND-enabling studies, biomarker discovery and companion diagnostics development. The ideal candidate is an individual that enjoys a fast-paced and dynamic work environment, with a demonstrated ability to work collaboratively to support project goals and objectives.

The role will require deep scientific and therapeutic-area expertise in Discovery Immunology, thorough familiarity and experience with the principles of drug development to ensure compound transition along the pipeline, management experience, and importantly the ability to work with ambiguity and embrace uncertainty. The role will demand critical, timely, independent decision making and requires a high degree of autonomy.

This leader must have scientific excellence in Immunology with a rich understanding of drug development, leadership, recruitment capabilities, management skills to direct a group of individuals, and excellent communication and collaboration skills to deliver on the therapeutic area strategy.

Qualifications

• PhD or equivalent post-graduate degree in Immunology or related field with 8 years or more of experience in academia and industry, preferably in the field of auto-immune diseases.
• Prior industry experience in Discovery Immunology required.
• Prior people management experience.
• Prior experience leading project teams and managing CROs/vendors.
• Direct experience working with immunology, inflammation and immune-mediated fibrotic diseases (Skin, Gut or Lung) or relevant molecular pathways.
• Experience in early drug discovery with proven leadership of preclinical development of therapeutic project(s) and clinical candidate selection is a requirement.
• Self-starter with strong scientific curiosity and rigor, excellent interpersonal and analytic skills, high ethical standards, and outstanding written and verbal communication skills.
• A desire to be part of a highly innovative, dynamic, and growing company aimed at developing novel therapeutics for patients.
• Demonstrable ability and enthusiasm for identifying, setting, and meeting critical deliverables, delivering clinical candidates into development.
• Track record of developing efficient discovery processes and leading complex cross-functional team collaborations, including managing relationships with internal and external collaborators.
• Proven track record of advancing programs through discovery, IND-enabling studies, and IND filing.
• Ability to build strong relationships with key stakeholders.

The expected base pay range for this position is $150,000 – $225,000 plus bonus, equity, and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. This range may be modified in the future.

All qualified applicants are considered for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran status or other protected class.

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