Postdoctoral Scientist - Transdermal Delivery (DDCS)

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview:

The Drug Delivery and New Product Innovation group within Lilly’s DDCS (Delivery and Device Connected Solutions) function studies physiological barriers across various routes of administration to apply and create novel patient centric drug delivery solutions.   With a broad focus to develop injection device platforms and novel delivery devices to improve patient care, the group focuses in serving as a center of excellence in the following areas:

• Injection physiology and new device ideation

• Novel routes of administration/new modalities

• Drug delivery of new modalities (such as nucleic acid therapeutics), monoclonal antibodies, synthetic peptides, and small molecules

• Digital biomarkers and nanomedicine

We are seeking a highly motivated, skilled, and creative scientific/engineering post doc to contribute to projects that operate at the interface of devices, drug products, and physiology.  As the Lilly molecule portfolio expands, our team will complement our molecule and formulation colleagues with engineering expertise to understand how devices and procedures can be designed to optimally deliver medicines across the transdermal interface. Our ideal teammate, motivated by curiosity, will explore and contribute to establishing first principles of delivery, shine as an inclusive member of a highly multi-disciplinary environment, and relentlessly pursue creative solutions for patients. They must be an effective collaborator with many different constituents including local team members, Lilly colleagues in Cambridge, external partners, and industrial and academic collaborators.

Responsibilities:

• Plan and implement transdermal drug delivery and device projects that involve materials, chemistry, and biological expertise

• Support the creation and development of critical laboratory capability for transdermal delivery device prototyping, formulation, and performance testing

• Oversee, design, and execute preclinical and clinical studies for transdermal delivery systems to increase fundamental knowledge and inform delivery device design based on PK, dose, and ADME information.

• Connect across Lilly organizations to ensure device and delivery programs in transdermal are integrated with therapeutic areas and PRD development teams

• Understand IP, freedom to operate, and competitive landscape in targeted areas of research

• Identify, evaluate, and monitor external delivery technologies in the transdermal space, build business case, and drive appropriate partnerships

• Ability to plan and execute flux studies, understanding processing of various skin types, knowledge of test required to understand barrier properties of skin,

• Ability to understand structure and transport of molecule.  In silico work exposure, role of permeation enhancers

• Ability to carry out high throughput screening of transdermal flux studies and flux calculations.

Basic Requirements:

• Hands-on research experience developing transdermal products such as patches and microneedle systems including skills related to prototyping drug-in-adhesive formulations, high-throughput screening, flux performance measurements, and associated analytical method knowledge.

• PhD in Biomedical, Materials, Controlled Release, Colloidal Systems, or Chemical Engineering or related fields preferred.

Additional Skills/Preferences:

• Effective technical writing, verbal communication, and presentation skills

• Desire and ability to coach/mentor engineering talent

• Strong communication skills and the ability to be an inclusive leader/colleague in a highly interdisciplinary environment

• Familiarity with small molecule and large molecule medicines and related physiology

• Experience designing and performing pre-clinical and/or clinical studies

• Familiarity with medical device regulatory environment and principles

About Eli Lilly’s Postdoctoral Scientist Program
 

When it comes to research and development, our goal is to discover and deliver innovative medicines that make life better for people around the world. It’s challenging, expensive, and often filled with failure. But even when we fail, we advance medical science and understanding by learning more about diseases, biology, and chemistry – ultimately bringing new solutions one step closer to reality.

Over the course of our history, we have shed light on some of the toughest health care problems known to man – diabetes, heart disease, infectious diseases, neuroscience disorders, cancer, and more. We could not pursue this without our research and development team.

Postdoctoral scientists help us continue this pursuit. During your experience you will get:

• Top industry research experience

• Mentoring by some of Lilly’s top scientists  

• Laboratory and classroom training and education to further your development

• Collaboration and networking across dozens of postdoctoral scientists and other researchers

Additional Information

• This position is not permanent. It is for a fixed duration of two years with potential to extend to 4 years. You will have opportunities to apply for full time positions after your duration is complete.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

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Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

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