Senior Scientist 2, Biology

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.

Position 

We are seeking a highly skilled and motivated Senior Scientist 2, Biology, to join our dynamic research team. In this role, you will play a central role in advancing our mission by leading the design, execution, and analysis of intricate experiments that bridge the realms of biology and technology. As a Senior Scientist 2, you will have the unique opportunity to drive cross-functional collaborations, lead impactful research initiatives, and contribute to the development of innovative solutions.

About You 

The ideal candidate for this role is an experienced scientific leader with robust qualifications. The candidate will serve as a leader in functional genomics, Target identification, and validation. They will provide critical support for multiple therapeutic areas including Oncology, Immunology, and Neuroscience. The candidate is expected to be proficient in executions and data analysis of multiple Omics-based experiments. Their strong analytical skills enable them to derive, interpret, and effectively communicate complex scientific insights. With excellent communication skills and a proven track record of leadership and collaboration within multidisciplinary teams, they are proactive, adaptable, and responsive to evolving research priorities and challenges.

What You’ll Do

• Design, execute, and analyze high-throughput “Omics” experiments including CRISPR screens and RNA and DNA-seq to identify genes involved in disease pathways and conduct MoA studies for pathway inhibitors.
• Proficient in routine bioinformatics analysis and interpretation including RNA-Seq, DNA-seq, CHIP-seq etc.)
• Integrate functional genomics data with other omics datasets to generate comprehensive biological insights and identify and prioritize potential novel therapeutic targets.
• Design and perform follow-up experiments to validate identified targets using a variety of molecular and cellular biology techniques.
• Collaborate with cross-functional teams including bioinformaticians, biologists, and chemists to advance research projects.
• Develop and implement innovative Omics methodologies to address challenging biological questions
• Present research findings to internal teams and at scientific conferences.

Qualifications

• Postdoc Fellowship plus 4 years of relevant experience or Ph.D. plus 7 years of relevant experience, or a Master’s degree plus 16 years of relevant experience or a Bachelor’s degree plus 18 years of relevant experience in Biology, Bioengineering, Biotechnology, or a closely related field, with substantial hands-on research experience. 
• Proficiency in designing and conducting CRISPR screens including CRISPR knockout (CRISPR KO), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa) including library design, delivery methods, and data analysis.
• Design and perform experiments involving high-throughput sequencing (e.g., DNA-seq, RNA-seq), and other omics techniques
• Strong background in molecular and cellular biology techniques.
• Experience with bioinformatics analysis tools and software for analyses of high-throughput sequencing data.
• Familiarity with statistical methods and tools used in genetic screen analysis (e.g., R, Python, MATLAB).
• Excellent problem-solving skills and the ability to work independently and collaboratively.
• Excellent communication skills, enabling clear conveyance of scientific concepts to diverse audiences.
• Proven leadership capabilities, with a track record of effectively leading and collaborating within multidisciplinary teams.
• Proactive, adaptable, and responsive to evolving research priorities and challenges.
• Strong analytical skills and the ability to derive, interpret, and communicate complex scientific insights effectively.

At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:​

• 401k plan with company matching​
• Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)​
• Mental health and wellness benefits​
• Weeklong summer and winter holiday shutdowns​
• Generous paid time off and holiday policies​
• Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee-paid life/AD&D policies ​
• Enhanced parental leave benefit​
• Daily subsidized lunch program when on-site​

The expected salary range for this role is $152,000 to $166,250 depending on skills, competency, and the market demand for your expertise.

Eikon is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

In accordance with the Company’s duty to provide and maintain a safe workplace, the Company requires all employees to be Fully Vaccinated with one of the FDA approved COVID-19 vaccines, which includes those vaccines that have received the FDA’s emergency use authorization. You will be expected to be Fully Vaccinated as of your Start Date. If you believe that you are exempt from this requirement under an applicable law or regulations, including Americans with Disabilities Act and California’s Fair Employment and Housing Act, you will need to contact the Company’s Human Resources group. For purposes of this section, Fully Vaccinated means (i) the completion of the vaccination regimen as approved by the FDA (by way of example, 2 doses of the Pfizer or Moderna vaccine and 1 dose of the Johnson and Johnson vaccine), and (ii) timely receiving booster vaccination, as recommended by the Centers for Disease Control and Prevention.

We are currently not accepting any new third-party agencies or firms at this time. Please do not forward unsolicited agency resumes to our website, employees or Human Resources. Eikon Therapeutics will not pay fees to any third-party agency or firm associated with unsolicited resumes.