Scientist, Discovery Immunology

(San Diego, CA)

Mirador is a next-generation precision medicine company focused on immunology and inflammation. The company’s Mirador360 ^TM precision development engine leverages the latest advances in human genetics and cutting-edge data science to rapidly advance new precision medicines for patients living with chronic immune-mediated inflammatory and fibrotic diseases. Launched in 2024, Mirador has raised over $400 million from leading life sciences investors and is based in San Diego, CA.

Summary

We seek a motivated, detail-oriented Scientist, Discovery Immunology with strong background in immunology / cell biology and experience developing cell-based assays to support our efforts in target validation, early phase antibody drug discovery, IND-enabling studies, biomarker discovery and companion diagnostics development. The ideal candidate is an individual that enjoys a fast-paced and dynamic work environment, with a demonstrated ability to work collaboratively to support project goals and objectives.

The role will require deep scientific and therapeutic-area expertise in Discovery Immunology, thorough familiarity and experience with the principles of drug development to ensure compound transition along the pipeline, management experience, and importantly the ability to work with ambiguity and embrace uncertainty.

Key Duties and Responsibilities

• Conceptualize and perform cell-based functional assays (cell lines, primary cells, whole blood) to support target validation, antibody drug screening, mechanism of action studies, biomarker identification and/or companion diagnostics development
• Work on preclinical and IND-enabling in vitro studies
• Analyze, critically interpret data and share results to project teams as required
• Keep meticulous records of experiments performed and maintain ELN entries
• Work collaborative with other scientists in the group in a highly matrixed lab environment

Education and Experience

• Bachelor’s degree with 8 or more years, Master’s degree with 6 or more years or PhD with 2 or more years experience in the biotech or pharmaceutical industry.
• Direct experience working with immunology, inflammation and immune-mediated fibrotic diseases (Skin, Gut or Lung) or relevant molecular pathways.
• Experience in early drug discovery with proven leadership of preclinical development of therapeutic project(s) and clinical candidate selection is a requirement.
• Self-starter with strong scientific curiosity and rigor, excellent interpersonal and analytic skills, high ethical standards, and outstanding written and verbal communication skills.
• A desire to be part of a highly innovative, dynamic, and growing company aimed at developing novel therapeutics for patients.
• Demonstrable ability and enthusiasm for identifying, setting, and meeting critical deliverables, delivering clinical candidates into development.
• Track record of developing efficient discovery processes and leading complex cross-functional team collaborations, including managing relationships with internal and external collaborators.
• Proven track record of advancing programs through discovery, IND-enabling studies, and IND filing.
• Ability to build strong relationships with key stakeholders.

Skills and Abilities

• Independent self-motivated life scientist that can generate scientific questions and design experiments to address them
• Energetic, curious and rigorous
• Excellent problem-solving and organizational skills
• Strong interpersonal and communication skills including presenting data to all levels of the organization
• Scientific rigor and curiosity to address scientific questions and design experiments to test working hypothesis
• Ability to work in fast-paced and matrix environment to meet project goals
• Proficiency in data analysis using Excel, GraphPad Prism, Flow Jo is required

The expected base pay range for this position is $100,000 – $135,000 plus bonus, equity, and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. This range may be modified in the future.

All qualified applicants are considered for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran status or other protected class.