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Senior Research Associate, Potency Assays for Cell Therapy

Employer
Adicet Bio, Inc.
Location
Redwood City, CA
Start date
Jul 8, 2024
View moreView less
Discipline
Regulatory, Science/R&D, Biotherapeutics, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

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Adicet Bio, Inc. is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer. Adicet is advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CARs) and adaptors (CAds), to enhance selective tumor targeting and facilitate innate and adaptive anti-tumor immune response for durable activity in patients.  For more information, please visit our website at https://www.adicetbio.com.

Senior Clinical Research Associate, Potency Assays for Cell Therapy

 

This role of  Senior Research Associate for the Analytical Development (AD) position will be responsible for the execution of routine testing, including but not limited to cell-based/potency assays used to characterize or release engineered CAR-T cell drug products.

Key responsibilities include: 

  • Contribute to assay design and development for release and in-process testing of CAR-T cell therapies with focus on cell-based potency assays and immunoassays.
  • Work closely with the Manager and other cross-functional team members and assist in efficient assay transfers between internal teams.
  • Maintain cell cultures of critical cell lines and generates/characterizes new cell banks.
  • Maintain electronic lab notebook and participate in writing and revising test methods, SOPs and/or other documents as appropriate.
  • Assist in everyday operation of analytical laboratories, including but not limited to equipment management and reagent inventory.
  • Assist in building result datasets for data visualization and communicate the same to AD and other technical operations team members as appropriate.

Qualifications:

  • Bachelor’s or Master’s degree with background in immunology, cellular, or molecular biology, or related fields of life sciences.
  • Master’s Degree with minimum 1 years’ experience or bachelor’s degree with 2 to 3 years' experience in a relevant academic or industrial lab setting required.
  • Hands-on experience in cell culture in a BSL-2 environment is required.
  • Experience in cell-based experiments, such as cytotoxicity or proliferation assays is strongly desired.
  • Experience in immunoassays, such as ELISA or Luminex is desired.
  • Excellent verbal and written communication skills.
  • Ability to work independently, multitask, and meet deadlines in a fast-paced environment
  • Highly motivated, organized, and disciplined record keeping; strong attention to detail.
  • Candidates having prior experience in cell-based/potency assay will be given the strongest preference.
  • Experience in cell therapy or multi-color flow cytometry is a plus.
  • Experience in gene therapy or molecular biology assays (qPCR/dPCR) is a plus

 

Salary Range: $101,000 - $140, 000

Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

 

 

Pay Range$104,000—$140,000 USD

At Adicet, our people are our greatest focus. We believe that attracting and retaining the best and brightest is the key to achieving our mission to deliver best-in-class gamma delta T cell therapies for patients fighting cancer.

Adicet is located in a state-of-the-art facility and works to create an incredible office experience with an onsite gym and various other fitness options, abundant, zero-cost, onsite parking with electric vehicle charging stations and free shuttle (Caltrain), company subsidized lunches (delivered onsite daily) and fully stocked breakrooms.

In compliance with California’s pay transparency law and in pursuit of pay equity and fairness, we publish salary ranges for all open positions. The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to, their qualifications (education, experience, specialty, and training), and peer and market data. This listed salary range represents the Company’s good faith and reasonable estimate of the range of possible compensation at the time of posting.

Company

Adicet Bio, Inc. is a privately held, pre-clinical stage biotechnology company developing novel universal immune cell therapies based on gamma delta T cells engineered with Chimeric Antigen Receptors.  Adicet is also focused on identifying and validating cancer specific targets directed to the intracellular proteome and then generating T Cell Receptor-like monoclonal antibodies (TCRLs) directed to these cancer-specific peptide targets presented by MHC Class I complexes. These TCRLs are being used to arm T cells or as T cell engagers in solid tumors. In August 2016, Adicet entered into a strategic collaboration with Regeneron Pharmaceuticals, Inc. to develop next-generation engineered immune-cell therapeutics using Adicet's gamma delta T cell allogeneic platform technology.
 
For more information, please visit our website at http://www.adicetbio.com.

Company info
Website
Location
1000 Bridge Parkway
Redwood City
California
94065
US

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