Associate, Early Portfolio Management

The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.

Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45 and 50 skipping amenable. We have also partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

You operate independently, are highly organized, and can anticipate the team’s needs. You enjoy working cross-functionally and do so successfully with an interpersonal acumen to build working relationships and drive collaborative initiatives. You have a strong scientific background, are naturally inquisitive, connect problems with solutions, and maintain the ability to pivot to meet changing priorities in a fast-paced environment.

The Opportunity

Entrada Therapeutics is hiring an Associate, Portfolio Management. This individual will collaborate closely with R&D to lead early-stage program planning (through clinical candidate selection) and participate as a key business partner and resource for related operational planning.

This role will be responsible for supporting the management and advancement of early-stage activities with an emphasis on cross-functional strategy and alignment with operational plans. Reporting to the Director of Early Portfolio Management, this position will bridge Entrada’s R&D, Business, and Operation teams to drive the successful development and expansion of our Portfolio

Responsibilities

Early Portfolio Planning

• In collaboration with research program teams, develop comprehensive discovery plans and monitor progress to ensure timely achievement of milestones.
• Support progress of early-stage discovery programs to clinical candidate selection by maintaining project plans that include strategies, timelines, optimization of scope, tradeoffs, resources, and risks.
• Proactively identify and raise project challenges and risks, propose contingency plans, and monitor execution of corrective actions.
• Provide operational support to scientific teams in execution of external collaborations (Academic labs, CROs, etc.).
• Organize high quality documents and presentations, roadmaps, deliverables, and updates as needed to support R&D program meetings.
• Facilitate open communication and cross-functional collaboration across research teams.

Early Portfolio Governance and Operations

• Implement early-stage program stage-gate processes in support of broader portfolio goals and milestone achievements.
• Partner with Discovery teams in developing and maintaining program-level budgets.
• Support operational initiatives across key pillars of Entrada’s business (e.g., R&D, Business Development/Strategy, HR, Finance, Operations, Communications).
• Support development of core capabilities that can support cross-portfolio

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

• Humanity - We genuinely care about patients and about one another.
• Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
• Creativity - We are creative problem solvers.
• Collaboration - We are more than the sum of our parts.
• Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

• Bachelor’s or advanced degree in life sciences, with 5+ years of relevant biotech industry experience.
• Strong scientific background, with working knowledge of drug discovery and development processes.
• Experience with Smartsheet is strongly preferred.
• Responsive and proactive, readily prioritizes to drive decision-making, and motivate teams.
• Ability to adapt to changing priorities and deadlines in a highly matrixed organization.
• Strong organizational, analytical, and problem-solving skills.

The Perks

By becoming a team member here at Entrada, you’ll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

Privacy Statement

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