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Senior Director, IT Infrastructure & Security

Day One Biopharmaceuticals
Hybrid - Brisbane, CA
Start date
Jun 15, 2024

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Information Technology
Required Education
Bachelors Degree
Position Type
Full time
Biotech Bay

Job Details

Day One Biopharmaceuticals is an emerging, mission-driven, drug development company intentionally designed to identify, clinically evaluate, and successfully commercialize novel treatments for pediatric oncology patients, and ultimately to expand those benefits to patients of all ages. For more information, please visit our website at

We are looking for a Senior Director, IT Infrastructure & Security to lead the team. This role will report directly to the VP, IT. This individual will provide vision and strategic leadership to deliver on the Infrastructure, Service Desk, and Information Security initiatives to ensure they align to the business objectives and growth strategy. The individual will work closely with the business partners, external vendors, and peers within IT to mesh technology and processes into innovative solutions to ensure stability, scalability, and availability of all infrastructure services. The candidate will have deep infrastructure engineer experience, strong cybersecurity understanding, technical leadership experience, and managing communication as well as expectations with cross-functional leaders and management team. This is a hybrid position (3-days onsite in Brisbane HQ, 2-days remote).

·       Lead the technology infrastructure strategy and execution for the enterprise
·       Develop, plan, and implement a robust information security program for the organization
·       Evolve and implement IT infrastructure, network operation, and end-user support strategy to align with business objectives
·       Provide leadership and guidance to the service desk team to ensure customer interactions are resolved in a timely and professional manner
·       Review, develop and enhance existing information technology policies
·       Works closely with and manage strategic vendor partner relationships
·       Partner with business leaders to develop roadmaps for IT areas including Infrastructure and information security
·       Prepare, monitor, and control the annual department budget to ensure expenditure is in line with the business plan
·       Drive culture of continuous improvement to improve quality, efficiencies, and standards across the infrastructure organization
·       Ensure corporate infrastructure and services are secure, scalable, flexible, and compliant
·       Evolves the 3-year IT Roadmap and system inventory, aligning them with the budget process
·       Prepares system configuration and deployment cost estimates, budgets, and schedules
·       Prepares and presents project proposals to management and business partners
·       Leads and facilitates the evaluation / recommendation of new technologies or capabilities that can be applied across the business
·       Conducts ongoing research into industry and technology trends. Evaluates, summarizes, and presents key trends with potential to impact IT capabilities
·       Partners with 3rd party vendors to understand and plan for application technology roadmaps and support services
·       Minimum 12 plus years’ work experience, including at least 10 years in a managerial/leadership role
·       Experience with infrastructure security assurance of user endpoints, servers, storage, IaaS, and networks
·       Experience with comprehensive disaster recovery architecture and operations, including storage area network and redundant, highly available server and network architectures
·       Experience with the following technologies: M365, Zoom, Druva, ServiceNow, Cisco Meraki, Cloud (Azure, AWS)
·       Experience working with security tools, or similar: Okta, Addigy, Netskope, Sentinel One, Avanan, Automox, Rapid7
·       Familiarity with security frameworks, standards, and regulations (e.g., NIST, ISO, GDPR, HIPAA)
·       Broad IT management experience, with emphasis on Life Sciences-related systems delivery required
·       Experience with the use of SDLC methodologies in project delivery required
·       Understanding of GxP controls, experience in an FDA-regulated environment is required
·       Ability to work directly with business partners and end users to generate consensus around technical directions
·       Ability to hire, develop, and retain critical staff
·       Ability to analyze complex business problems and evaluate solutions
·       Ability to translate complex technical issues into business terms
·       Contributes to setting the overall IT department agenda and operating practices
·       Works to develop well-rounded personnel via complete and actionable development plans
·       Excellent interpersonal, communication, and business partnering skills
·       Superior organization, planning, and project management skills
·       Strategic mindset with strong analytical foundation
·       Strong communication, negotiation, and presentation skills – verbal and written are required
·       Ability to drive continuous improvement across the organization
·       Ability to facilitate and resolve conflicts at both the senior leaders and management team
·       Ability to operate in a cross-functional and matrix environment.
·       Excellent executive presence
·       High level of personal integrity consistent with Day One Biopharmaceutical’s values
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification.
The salary range for this position is $260,000 - $280,000. Day One considers a range of factors when determining base compensation. These considerations mean actual compensation will vary.
Please visit to see our competitive benefits.

Day One Biopharmaceuticals is committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law.
Employment is conditioned upon full vaccination from the COVID-19 virus, including submission of documented proof thereof, as of the start date.  Day One Biopharmaceuticals will comply with applicable law regarding the reasonable accommodation of individuals who are not vaccinated because of a disability and/or a sincerely held religious belief.

We are unable to sponsor or take over sponsorship of any applicant work visas at this time.
Recruitment & Staffing Agencies: Day One Biopharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Day One Biopharmaceuticals or its employees is strictly prohibited unless contacted directly by Day One Biopharmaceutical’s internal HR team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Day One Biopharmaceuticals, and Day One Biopharmaceuticals will not owe any referral or other fees with respect thereto.



Day One Biopharmaceuticals understands that advances in cancer research now enable drug developers to identify children and adults who may benefit from the same medicine. We are a unique company created to find and develop new therapies that meet the critical needs of people of all ages living with cancer – starting from the biology of childhood cancer. Our distinctive approach, together with our trusted network of pediatric oncology investigators, gives us an unparalleled ability to advance promising discoveries for patients of any age. We are ready to pursue the full potential of our therapies to improve the greatest number of lives as quickly as possible.

Company info
2000 Sierra Point Parkway
Suite 501

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