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Senior Bioinformatics Software Engineer

Employer
Life Edit Therapeutics
Location
Durham, NC
Start date
Jun 8, 2024

View more

Discipline
Engineering, Information Technology, Bioinformatics, Science/R&D
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Bio NC

Job Details

 

The Role:

The Bioinformatics and Computational Biology group at Life Edit supports and interacts with all areas of the company. We are looking for a motivated bioinformatics software engineer to help process and analyze large datasets related to gene editing experiments. We are seeking curious, enthusiastic, competent, and self-motivated individuals with strong emotional intelligence to work in our company. A willingness to embrace our cultural values will be critical for success in this role. This is an exciting opportunity to help build a successful therapeutics company from an early stage. Life Edit Therapeutics Inc. is a dynamic, high-growth, and intellectually challenging workplace with projects that span discovery and development of novel gene editing tools to therapeutic applications for clinical indications.

Here’s What You’ll Do:

  • Develop, optimize and maintain bioinformatics workflows for the analysis and interpretation of gene editing data, including short and long read next-generation-sequencing (NGS) data produced by various assays
  • Develop, maintain and provide support for applications used for delivery, visualization and interpretation of data by users
  • Ensure scientific rigor and reproducibility by implementing and following best practices in software development, code versioning, software testing and deployment
  • Gather requirements, communicate results and provide support to various stakeholders throughout the company

Required Qualifications:

  • Bachelor's, Master's or Ph.D. degree or equivalent practical experience
  • Strong expertise using Python for general programming, data analysis and visualization
  • Familiarity with software engineering best practices such as unit testing, version control, CI/CD, modular design, refactoring, design patterns, etc.
  • Knowledge of bioinformatics workflow tools such as Nextflow, Snakemake, WDL or similar and experience with containerization technologies such as Docker or Singularity
  • Experience with Cloud Computing and UNIX/Linux environments
  • Familiarity with relational databases and SQL
  • Strong communication skills both written and oral

Preferred Qualifications:

  • Familiarity with the AWS ecosystem
  • Experience deploying and supporting cloud-based production software environments
  • Expertise in one or more of Rust, Go, Java, C/C++ or similar programming language
  • Knowledge of Infrastructure as Code (i.e., AWS Cloud Formation, CDK, Terraform, etc)
  • User Interface development / data delivery experience with one or more of Plotly Dash, Tableau, Streamlit, QuickSight, HTML/JavaScript frameworks or similar
  • Experience analyzing Next Generation Sequencing (NGS) data
  • Exposure to CRISPR gene editing data analysis
  • Knowledge of data warehousing tools and best practices
  • Experience performing statistical analysis
  • Practical exposure to Machine Learning and AI

Why join Life Edit and the ElevateBio ecosystem?

Life Edit Therapeutics is an integrated subsidiary of ElevateBio, a technology-driven cell and gene therapy company that is accelerating access to the cutting-edge technologies and expertise that can change the future of medicine. Our integrated model combines multiple R&D technology platforms – including Life Edit gene editing – and cGMP manufacturing to power the discovery and development of advanced therapeutics. Our ecosystem is designed to enhance speed, delivery, and probability of success to change patient lives.

Life Edit is an integral part of ElevateBio’s ecosystem of platform technologies and is pioneering focused next-generation gene editing technologies and therapeutics. Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA. Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies. We are looking for a unique individual who can continue to lead the cultural development of Life Edit and build on its momentum as an integral part of the ElevateBio ecosystem.

Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.

Our Vision:
We seek to be the world’s most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.

ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Company

Life Edit Therapeutics is an ElevateBio company focused on advancing next-generation gene editing technologies and therapeutics. Life Edit has built a highly innovative platform with one of the world’s largest and most diverse libraries of RNA-guided nucleases (RGNs), base editors, and reverse transcriptase (RT) editors that provide flexible editing and unprecedented access to the genome. The platform allows Life Edit to target any genomic sequence and potentially develop novel human therapeutics for the most challenging genetic diseases by enabling ex vivo engineering for cell therapies and regenerative medicines and in vivo delivery of gene therapies.

Company info
Website
Location
300 Morris Street, Suite 300
Durham
NC
27701
US

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