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Executive Director - Program Portfolio Management (Therapeutics & Oncology)

Moderna, Inc.
Cambridge, MA
Start date
Jun 6, 2024

View more

Science/R&D, Oncology
Required Education
Bachelors Degree
Position Type
Full time
Genetown, Best Places to Work

Job Details

The Role:

Moderna's Portfolio & Program Management Dpt. seeks an Executive Director PPM with strategic focus on our Therapeutics & Oncology (T&O) portfolio and programs, incl. INT and Rare Disease. This leader will oversee development programs from IND to licensure, ensuring the successful execution of our programs and strategic objectives in the Therapeutics & Oncology area. Collaborating closely with Program Leaders, this role will integrate cross-functional teams to deliver transformative mRNA therapies, with the flexibility to support additional therapeutic areas as needed.

Key Responsibilities:

  • Oversees cross-functional planning and execution of T&O programs, incl. definition of operational strategy, management of timelines, risk assessment and mitigation, cost and quality to secure approval of new drugs and new indications across the product portfolio (life cycle management) in close collaboration with Program Leaders.

  • Collaborates closely with T&O Development leadership contributing to the T&O portfolio strategy.

  • Drives and oversees the T&O portfolio execution and proactively identifies and escalates systemic issues which require action.

  • Drives and contributes to decision-making processes for infectious disease programs at the Program, T&O Development Unit, Governance and Enterprise level.

  • Builds and maintains strong relationships with stakeholders, ensuring T&O program alignment with functional and corporate goals.

  • Manages the T&O program budgets in collaboration with the R&D Finance team, optimizing resource allocation.

  • Ensures that PM deliverables are available and accurate to support regular enterprise processes, e.g. portfolio reporting, strategic portfolio reviews, long range financial planning, budget and resource planning.

  • Drive the strategic and operational integration of development initiatives, aligning with leadership, stakeholders, and enterprise priorities and customize them to the unique needs of T&O development.

  • Leads and/or acts as change agent for continuous improvement/
    transformational initiatives within PPM, Development or at the enterprise level.

  • Demonstrates significant agility by being able to readily pivot to support new program teams, new therapeutic areas and/or manage diversity in program types with skill and ease.

  • Leads, mentors, and guides development of PM talent, which includes succession, development planning, performance management, and recognition of the T&O PM team.

  • Acts as a key member of the PPM leadership team and ensures integration and connectivity of all PPM efforts with evolving Enterprise strategies.


  • Extensive experience in drug development, preferably in Oncology and/or Rare Disease development, with a Bachelor's degree and a minimum of 15 years, or a Graduate degree with 10+ years in a scientific field, incl. 8-10 years in program and portfolio management.

  • Subject matter expertise in the end-to-end R&D process, particularly in late-stage drug development, submission, and lifecycle management.

  • Exceptional interpersonal, communication, presentation and organizational skills to effectively manage, advance development programs and influence decisions.

  • Proven success in leading cross-functional teams and managing complex programs preferably in the Oncology and/or Rare Disease domain(s).

  • Proficiency in program management tools and software.

Preferred Qualifications:

  • Advanced degree (PhD, PharmD) and project/program management training or certification preferably with an emphasis on Oncology and/or Rare Disease.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary year-end shutdown
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, theinfrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our peopleare the driving force behind our scientific progress and our culture.Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. Were focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at (EEO/AAP Employer)



Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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Company info
200 Technology Square
Cambridge, MA

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