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Chief Human Resources Officer Senior Vice President /VP, Human Resources

Annexon, Inc.
South San Francisco, California
Start date
May 21, 2024

View more

Administration, Human Resources/Recruiting
Required Education
Bachelors Degree
Position Type
Full time
Biotech Bay

Job Details

Work Location

Corporate Headquarters (South San Francisco, CA) – Hybrid

Position Summary

Annexon is seeking an experienced CHRO/SVP/VP of Human Resources to design and execute a human resources strategy in alignment with the Annexon’s overall company objectives.  The CHRO/SVP/VP of HR will collaborate with the CEO and partner with the executive team to develop a strategic workforce plan coupled with an effective and efficient plan spanning employee hiring, engagement, development and retention as Annexon continues to evolve.  Like all Annexon leaders, the successful candidate will have a deep-rooted commitment to serving patients and a passion for transforming the lives of people with serious diseases and their families. Successful candidate will exhibit depth and acumen in the following key areas:

  • Create and Execute a Talent Strategy – Human Resources will be responsible for talent acquisition, employee engagement, total rewards, learning and development, organization development & effectiveness, diversity & inclusion and HR operations. The VP/SVP, Human Resources will ensure that we attract top talent, develop critical capabilities, and create the infrastructure that will enable our continued growth and development.
  • Act as a Trusted Advisor and Business Partner to the CEO and Company Leadership – the successful candidate will be an inspiring leader and mentor, functioning as the expert on people and organizational issues.
  • Organizational Development – Success in this role requires a strategic, collaborative thinker, who can offer a long-range vision for effectively scaling the Company with a tailored workforce plan consistent with Annexon’s business needs and values. The successful candidate will possess a strong mix of strategic and hands-on experience and thrive in a fast-paced, dynamic work environment. The CHRO/SVP/VP, Human Resources will be a key member of the leadership team while helping to build and scale the company through new phases of growth.
  • Culture Enhancer – partner with leadership and the employees to ensure a vibrant, entrepreneurial, collaborative, transparent, trusting and fun culture that embodies Annexon’s Core Values of Warrior Spirit, Sound Judgment, Passion, All For One and Thrive! Includes engaging with the Culture Club, being a formal and informal sounding board to employees.
  • Diversity Recruiting and Employee Retention - successful track record of hiring and retaining a diverse workforce. Embed diversity into Annexon’s DNA. Coach and provide guidance to leaders on building diverse teams where everyone feels welcome.


  • Reports to the CEO and is a recognized leader in the organization.
  • Excited about and a champion for building and operating an open, fast-paced, innovative and passionate biotech company focused on delivering game-changing therapies for patients.
  • With the CEO and CFO help to advise the compensation committee on the talent market in general as well as provide advice on key executive level hires.
  • Serve as a strategic compensation and total rewards coach to members of leadership team. Leverage data and analytics to advise on competitive compensation and incentive structures.
  • Manage compensation planning and benefits programs including policies, processes and Ensure the programs are market competitive and aligned with business and talent goals.
  • Attract, develop, and retain top tier talent across the company.
  • Work closely with the Leadership team as well as accounting/finance to develop workforce plans. Develop and oversee recruiting plans and efforts to identify top talent within and outside the organization and build employment brand in the talent marketplace.
  • Partner with leadership on organizational design; build capabilities needed to deliver on the business strategy and support high performance of the company.
  • Ensure talent programs and growth opportunities for team members and culture of continuous learning.
  • Oversee employee engagement and employee communications in collaboration with CEO/CFO.
  • Be accessible, approachable, and a capable resource to employees throughout the organization, establishing and maintaining strong relationships.
  • Advise and counsel managers on employee relations matters, including employee development and employee performance, team effectiveness and employee engagement.
  • Champion, promote, and guide the Company’s inclusion strategy and diversity initiatives.
  • Be a strategic leader of People operations, systems and processes that will support the organization as the company continues to grow and improve the overall effectiveness of the company.
  • Ensure compliance with all legal requirements and applicable labor laws.

Key Qualifications

  • Minimum of 15 years of progressively responsible, relevant people operations/human resources leadership experience, preferably in the pharmaceutical or biotechnology industry
  • Successful track record being a trusted advisor to the CEO and strategic business partner to the CEO and Company Leadership. Ideal candidate will have a minimum of 2 – 5 years in an executive HR leader role partnering with C-level executives.
  • Undergraduate degree in relevant field; advanced degree preferred
  • Experience scaling an organization and building teams while aligning the appropriate HR systems, processes and resources against a high growth business strategy. Especially important for the successful candidate to have prior experience supporting an organization’s organic growth by driving a highly successful talent acquisition strategy.
  • Proven experience in successfully in building and leading the People Ops function, including experience managing talent acquisition, total rewards, employee relations, learning and development, organization effectiveness, diversity & inclusion and HR operations in a growing organization
  • Track record of developing and implementing HR programs and initiatives that support strategic objectives within an innovative environment
  • Must demonstrate ability to initiate and lead strategic/proactive HR projects while still managing and providing day to day People Operations support
  • Outstanding communication skills, capable of presenting oral and written communications in a well-organized and compelling manner to management team colleagues, the board and external stakeholders
  • Strong business insight and analytical skills; adept at using metrics & data to inform and influence decisions
  • Expertise in coaching across the full spectrum of an organization and managing/mentoring a team
  • Superior interpersonal skills with the ability to develop strong, trusting relationships to gain support and achieve results
  • Executive presence and ability to lead and influence by example
  • Knowledge of California employment law and federal government compliance regulations


What Annexon offers 

  • Diversity, Equity, Inclusion, and Belonging are important to us. We believe that diversity, equity, inclusion and belonging are essential for the strength of our business and the vitality of the communities we serve. We continuously work to build our pipeline of underrepresented candidates for our workforce, enhance, recruit and develop a best-in-class, diverse, equitable and inclusive workforce; ensure that Black, LatinX and other underrepresented candidates have long-term sustainable opportunities to work with Annexon; and hold our vendors to the same standards under which we operate. To learn more about Annexon’s diversity commitment, culture and values, please visit
  • A stimulating and rewarding workplace includes flexible work schedules, remote opportunities and the ability to achieve a work-life balance.
  • We are located in Brisbane, CA, with shuttle service from BART, CalTrain and the Ferry.
  • Annexon offers a competitive base salary and equity participation, employee stock purchase plan, as well as a comprehensive health benefit package that includes medical, dental, vision, 401(k), flexible spending plans, as well as other benefit



The anticipated starting salary range for the Vice President, Human Resources position is $263,300 - $291,600 per year. The starting salary range for the Senior Vice President, Human Resources position is $310,600 - $341,400. The starting salary for this position will be determined based on the candidate’s education, experience, transferable skills, licenses/certifications, location, and will be reviewed on a case-by-case basis to determine the final compensation. The starting salary does not include any other potential components of the total compensation package, including bonus, equity, employer provided benefits, and perks.


Company Summary

Annexon Biosciences is a clinical-stage biopharmaceutical company seeking to bring game-changing medicines to patients with classical complement-mediated diseases of the body, brain and eye. The classical complement cascade is a seminal pathway within the immune system that anchors and drives a host of autoimmune, neurodegenerative and ophthalmic diseases. Annexon is advancing a new class of complement medicines targeting the early classical cascade and all downstream pathway components that contribute to disease, while selectively preserving the beneficial immune functions of other complement pathways. Annexon is rigorously developing a pipeline of diversified product candidates across multiple mid- to late-stage clinical trials, with clinical data anticipated throughout 2023 and beyond.


EEO Employer – Annexon highly values Diversity, Equity, Inclusion and Belonging

Annexon Biosciences is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment based on race, color, religion, national origin, age, gender, sex, ancestry, citizenship status, mental or physical disability, genetic information, sexual orientation, veteran status, or military status. We are proud to promote a work environment where everyone, from any background, can do their best work.


Staffing Agencies

Annexon Biosciences does not accept unsolicited agency resumes and will not pay fees to any third-party agency or firm that doesn’t have a signed agreement with Annexon Biosciences. Please do not send agency CVs/resumes through Annexon’s website or Annexon Employees.  Inquiries must be sent to with the Subject Heading:  Staffing Agency Request.


We’re passionate about bringing game-changing therapies to patients suffering from serious complement-mediated autoimmune, neurodegenerative and ophthalmic disorders.

CSO, Larry Mattheakis, Ph.D
CFO, Jennifer Lew

Company Ownership: Public
Stock Symbol: ANNX
Stock Exchange: NASDAQ

Company info
1400 Sierra Point Parkway
Building C, 2nd Floor

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