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Director, Health Economic and Outcomes Research

BioMarin Pharmaceutical Inc.
San Rafael, California
Start date
May 20, 2024

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Job Details

This role will lead the payer evidence strategy and execution for BioMarin’s pipeline programs. Key activities include: 

  • Lead development of the global payer evidence strategy
  • Lead HEOR evidence generation, synthesis and dissemination projects in collaboration with other functions including Clinical Sciences, Medical Affairs and Data Science
  • Shape the understanding of value of BioMarin’s early development programs and input the market access perspective into clinical development plans to ensure they meet payer needs


  • Plan, develop, synthesize and disseminate HEOR evidence to demonstrate the value of BioMarin’s pipeline assets
  • Represent market access in global cross-functional forums including the Integrated Evidence Team
  • Review clinical development plans including trial design, endpoints and analytical strategies to ensure they meet payer needs
  • Maintain knowledge of health technology assessment (HTA) policy and continue innovation in approaches to HTA in rare diseases
The role is part of the Global HEOR team which sits within Global Value Access & Strategic Pricing. It will include a high degree of cross functional collaboration with medical affairs, regulatory affairs, clinical sciences, data sciences, patient affairs and with regional and local market access teams. It will also involve liaising with external stakeholders including payers, HTA agencies and clinical and patient groups.  EDUCATION 
  • Bachelor’s degree in relevant field (e.g. pharmacy, medical science, science)
  • Post graduate qualifications (Masters or PhD) in public health, health economics, epidemiology or statistics preferred


  • Minimum 10 years of HEOR experience obtained from either a consulting or pharmaceutical industry background
  • Sound knowledge and experience of different payer architypes and appreciation for the broader market access environment – ideally gained across multiple countries
  • Rare disease experience is preferred
No responsibility for supervision. 


  • Excellent verbal and written communication, collaboration, influence, strategic, analytical and problem-solving skills are required
  • Demonstrated ability to manage a range of HEOR evidence projects including cost-effectiveness models, budget impact models, systematic literature reviews and real world data analysis
  • Ability to provide input into clinical program through input into trial designs, statistical analysis plans and study reports
  • Demonstrated ability to gain alignment of stakeholders including internally Commercial, Medical, Clinical and Regulatory departments and externally key decision makers, health economists, clinical experts and patient organizations
  • Working knowledge of common statistical packages and reference management software would be an advantage.
Note:  This description is not intended to be all-inclusive or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. 

Equal Opportunity Employer/Veterans/Disabled 

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. 


BioMarin is a global biotechnology company dedicated to transforming lives through genetic discovery. In 1997, the company was founded to make a big difference in small patient populations, focusing on giving much-needed attention to the underserved communities of those with rare diseases. BioMarin sought to help patients whose voices could not always be heard and treat conditions that were not always in mainstream medical conversations. Throughout its history, BioMarin has worked tirelessly to make a difference by pursuing bold science. The company’s first approved therapy was inspired by a father who refused to accept there was no therapy for his son’s rare diagnosis. That relentless pursuit to change the course of his son’s future through the power of science is at the core of who BioMarin is today.

Through the company’s expertise in genetics and molecular biology, BioMarin has developed eight first or best-in-class targeted therapies that address the root cause of the conditions it seeks to treat, helping to better the lives of those struggling with rare genetic disease. The company’s purposeful and scientifically precise team of physicians and scientists has honed each treatment modality to seek transformative therapies.

Now, BioMarin seeks to make an even greater impact by applying the same science-driven, patient-forward approach that propelled the last 25 plus years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Each drug candidate pursued is guided by a fundamental understanding of the genetics and underlying biology of the condition it will address. The company believes that applying its knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The more innovative solutions developed, the more lives BioMarin can impact.

Company info
United States

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