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Principal Software Engineer, Quality

Moderna, Inc.
Cambridge, MA
Start date
Mar 25, 2023

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Engineering, Quality, Quality Control
Required Education
Bachelors Degree
Position Type
Full time
Genetown, Best Places to Work

Job Details

The Role

Moderna is seeking a Principal Software Engineer who will be responsible for working to deliver software solutions as part of a scrum team to support Moderna's clinical development and manufacturing operations, including Personalized mRNA Cancer Vaccine (PCV). In this role, you will work directly with users to understand requirements and then work with your team to design, develop, deploy, and maintain custom software solutions.

The Clinical Informatics team is expanding a suite of custom applications focused on clinical trial design digitization to enable end to end forecasting + execution capabilities. You will have the opportunity to work with our Data Science & AI team to integrate their algorithms into production applications used by Moderna internally to model, plan, optimize, and execute our clinical trial pipeline in order to accelerate humanity's access to new mRNA medicines.

Heres What Youll Do

  • Work closely with product owners to understand business needs and design solutions.

  • Develop innovative and intuitive full-stack TypeScript/JavaScript web applications as part of a team to transform business processes.

  • Lead and drive quality engineering best practices and test strategies across multiple scrum teams.

  • Work to enhance the automation of load testing, performance testing, unit testing, API testing, etc.

  • Deploy and improve applications in a constantly evolving Cloud environment.

  • Monitor and analyze application performance, resilience, and quality.

  • Contribute to many different projects in a dynamic, fast-moving, agile environment.

Heres What Youll Need (Minimum Qualifications)

  • BS/BA degree in Computer Science or equivalent with 8 years of experience or MS with 5 years of experience; a combination of education and experience may be considered.

  • Experience with modern full-stack web application development.

  • Experience using Github/Bitbucket Pull Requests.

  • Experience creating beautiful UIs using HTML, CSS/SASS/etc., and modern JS libraries

  • Experience with Angular ^10.

  • Experience designing and testing RESTful HTTP APIs

  • Experience with Node.js

  • Experience using modern ORMs to query relational databases.

  • Experience with relational database models and writing SQL; preferably PostgreSQL.

  • Experience writing unit tests, component tests, and end-to-end tests; preferably Jest and Cypress.

  • Experience using AWS Cloud resources; e.g. S3, SNS/SQS, ElastiCache, etc.

  • Experience with the Agile operational practices.

  • Experience documenting technical systems and user workflows.

  • Experience communicating with application users to understand and collect their requirements and requests.

Heres What Youll Bring to the Table (Preferred Qualifications)

  • Experience working in Life Sciences, pharma/biotech, or related scientific field.

  • Experience in healthcare technology software development.

  • Experience leading SDETs.

  • Experience with containerization systems; preferably Docker and Kubernetes.

  • Experience with GxP, GAMP5, ISO, SOC2, or HITRUST

  • Expert knowledge in integrating automation frameworks into the CI/CD pipeline.

  • A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary year-end shutdown
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.




Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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Company info
200 Technology Square
Cambridge, MA

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